DISTRIBUTED 2D TEMPERATURE SENSING DURING NANOPARTICLES ASSISTED LASER ABLATION BY MEANS OF HIGH-SCATTERING FIBER SENSORS
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Date
2020-07-28
Authors
Ashikbayeva, Zhannat
Aitkulov, Arman
Jelbuldina, Madina
Issatayeva, Aizhan
Beisenova, Aidana
Molardi, Carlo
Saccomandi, Paola
Blanc, Wilfried
Inglezakis, Vassilis J.
Tosi, Daniele
Journal Title
Journal ISSN
Volume Title
Publisher
Nature Research
Abstract
The high demand in effective and minimally invasive cancer treatments, namely thermal ablation, leads to the demand for real-time multi-dimensional thermometry to evaluate the treatment effectiveness, which can be also assisted by the use of nanoparticles. We report the results of 20-nm gold and magnetic iron oxide nanoparticles-assisted laser ablation on a porcine liver phantom. The experimental set-up consisting of high-scattering nanoparticle-doped fibers was operated by means of a scattering–level multiplexing arrangement and interrogated via optical backscattered reflectometry, together with a solid-state laser diode operating at 980 nm. The multiplexed 2-dimensional fiber arrangement based on nanoparticle-doped fibers allowed an accurate superficial thermal map detected in real-time.
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Keywords
Research Subject Categories::TECHNOLOGY
Citation
Ashikbayeva, Z., Aitkulov, A., Jelbuldina, M., Issatayeva, A., Beisenova, A., Molardi, C., Saccomandi, P., Blanc, W., Inglezakis, V. J., & Tosi, D. (2020). Distributed 2D temperature sensing during nanoparticles assisted laser ablation by means of high-scattering fiber sensors. Scientific Reports, 10(1). https://doi.org/10.1038/s41598-020-69384-2