Abstract:
It is evident that saliva contains many biomarkers that may help in noninvasive diagnosis of many diseases. There is also a direct contact between saliva and oral cancer lesions that may be helpful in the early detection of lung cancer. This review represents different biosensors that are in use for various medical applications, which can be further utilized to detect cancers. However, specific, accurate, and high sensitive biosensors are required because the cancer biomarkers have less concentration in saliva. Patients suffering from lung cancer have some biomarkers that are not found in healthy patients and can be useful in the early detection of disease. Currently, a single method is not enough to detect lung cancer from saliva. So, in order to get true positive results, some considerations must be taken while interpreting results from biosensors. Moreover, a combination of other technologies and comparing results with healthy persons will allow us to diagnose lung cancer in the future.