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Browsing NU Research Week - II by Title

Browsing NU Research Week - II by Title

Now showing items 154-173 of 203

Regulation of asymmetric neurogenesis in c. elegans

Aldabergenova, A.; Poole, R. (Nazarbayev University, 2014)

Neural specification is further complicated when we consider that it needs to be coordinated across the left-right (L/R) axis. Disruptions in the bilaterally symmetric organization of the human brain are frequently ...
Representation of algebraic convex geometries

Adaricheva, K. (Nazarbayev University, 2014)

Convex geometry is a set system generated by the closure operator with the antiexchange axiom. These systems model the concept of convexity in various settings. They are also closely connected to anti-matroids, which are ...
Research of interconnected wind turbines with intelligent control

Ten, V.; Isembergenov, N.; Nikulin, V. (Nazarbayev University, 2014)

Development of renewable energy sources in Kazakhstan, including wind energy, brings the needs to design and develop control and integration to a power system. The aim of the Project is to design a power converter supplied ...
Research on the bio-distribution of interferon gamma-containing pharmacocytes

Ibrasheva, D.; Idrissova, D.; Umbayev, B.; Masoud, A.; Askarova, Sholpan (Nazarbayev University, 2014)

Viral hepatitis B and C- is a widespread infectious disease of the liver and is a potential threat to human life. Treatment of HCV and HBV requires prolonged (parenteral or oral) administration of antiviral and ...
Re-writing the russian conquest of Central Asia

Morrison, Alexander Stephen (Nazarbayev University, 2014)

Between 1845 and 1895 roughly 1,500,000 square miles of territory in Central Asia were added to the Russian empire. Russia's expansion southwards across the Kazakh steppe into the riverine oases of Turkestan was one of ...
Role of HSC70 protein in maintenance of endoplasmic reticulum CA2+ homeostasis

Khamzina, Y.; Nauryzbayeva, A.; Gilman, C. (Nazarbayev University, 2014)

Intracellular calcium homeostasis is disrupted in many neuronal diseases and traumatic brain injuries resulting in endoplasmic reticulum (ER) stress [1]. ER stress and intracellular calcium homeostasis is a hub of signaling ...
Role of ROS in AB42 mediated cell surface P-selectin expression and actin polymerization

Tsoy, A.; Askarova, Sholpan; Shalakhmetova, T.; Umbayev, B.; Adambekov, S.; Zhumadilov, Z. (Nazarbayev University, 2014)

Blood-brain barrier dysfunction plays an important role in the onset and progression of Alzheimer's disease (AD). In the AD brains an increased deposition of A(3 in the cerebral vasculature has been found to correlate ...
Screening mutation in RYR2 gene in a Kazakhstani idiopathic ventricular tachycardia study cohort: two novel mutations

Akilzhanova, A.; Guelly, C.; Abilova, Z. M.; Rakhimova, S.; Nuralinov, O. M.; Abdrakhmanov, A. C.; Bekbosynova, M. S. (Nazarbayev University, 2014)

The human ryanodine receptor 2 (RYR2) is one of the key players tightly regulating calcium efflux from the sarcoplasmic reticulum to the cytosol and found frequently mutated (<60%) in context of catecholaminergic polymorphic ...
Semiclassical gravitational collapse and avoidance of singularities

Malafarina, D. (Nazarbayev University, 2014)

General Relativity (GR) predicts that, under standard conditions for normal matter, when gravity prevails over other forces, a space-time singularity must form [1]. On the other hand singularities are not expected to ...
Semi-externalization, semi-internalization, misalignment costs, and CEOs' assessments of venture capitalists' support

Khanin, D.; Turel, O. (Nazarbayev University, 2014)

Advancing transaction costs economics (TCE), we propose that hybrids (e.g., alliances) may be preferred to markets and hierarchies whenever the benefits of semi-externalization (partial adoption of the market mode of ...
Simple time domain analysis of natural balancing in flying capacitor stacked multicell converters

Ornov, N.; Ruderman, A. (Nazarbayev University, 2014)

Stack Multicell Converters (SMC) is a class of converters derived from a classic Flying Capacitor Converter (FCC). The paper presents simple closed-form analysis of average capacitor natural voltage balancing dynamics ...
Simulation and design of nonlinear material structures for energy and biomedical devices

Wei, D.; Zhang, D.; Ko, W. L.; Skrzypacz, P. S.; Elgindi, M.; Liu, Y. (Nazarbayev University, 2014)

The project's main objective is the development of mathematical models and solutions of the models for simulation and design of some modern nonlinear material structures for energy and biomedical devices. One of the ...
SNX 9 interacts with dynamin 2 and N-wasp to regulate focal adhesion disassembly and cell migration

Zhubanchaliyev, A.; Chao, W. T.; Kunz, J. (Nazarbayev University, 2014)

The turnover of focal adhesions is essential for normal cell migration and tumor invasion, but the underlying mechanisms are poorly understood. We have previously shown that the disassembly of focal adhesions occurs by ...
Some basic BVPS for complex PDES method of reflection on example of two irregular domains

Shupeyeva, B. (Nazarbayev University, 2014)

The advantage of the method described is the fact that solution of the problems can be obtained analytically and presented in explicit form. This fact will be presented on example of two different irregular domains such ...
Split core technology allows efficient production of virus-like particles presenting a receptor-contacting epitope of human IgE

Baltabekova, A. Zh.; Shagyrova, Zh. S.; Voykov, M.; Ramanculov, E. M.; Shustov, A. V. (Nazarbayev University, 2014)

Immunoglobulin E (IgE) plays a central role in type I hypersensitivity including allergy and asthma. Novel treatment strategy envisages development of a therapeutic vaccine designed to elicit autologous blocking antibodies ...
Stability of small positronic atoms in ground and excited states

Bubin, S. (Nazarbayev University, 2014)

Studying the dynamical stability of positron-atom and positron-molecule complexes provides an insight into the physics and chemistry of low energy positrons and their interaction with matter. Beams of low energy positrons ...
Stand -alone net zero energy container houses as temporary offsite working/living

Kim, J. R.; Bakhtiyarov, D.; Saliyev, D.; Zhumabekov, G.; Sailauova, N. (Nazarbayev University, 2014)

This paper is aimed to investigate and briefly analyze the conditions in Kazakhstan to predict the effectiveness of operation of standalone net zero energy container house. The description of Kazakhstani weather conditions ...
Students' perceptions of the role of their NIS experience in their academic performance at Nazarbayev University

Almukhambetova, A. (Nazarbayev University, 2014)

Government support of gifted children in Kazakhstan is based in understanding human capital as a main component of the country's further successful economic development. In 2009, the government of Kazakhstan launched a ...
Study of aggregation of the 2', 7'-dichlorofluorescein dye caused by the intermolecular hydrogen bond

Balanay, M.; Fan-Hagenstein, H. (Nazarbayev University, 2014)

The project's main objective is to study the aggregation of the 2',7'-dichlorofluorescein dye molecule through intermolecular hydrogen bonding in various solvents. With two chromophores perpendicular to each other, ...
Subnanomolar detection of tuberculosis biomarker MPT64 in sandwich sers immunoassay on novel low -cost substrate

Ralchenko, Y.; Khamkhash, L.; Bukasov, R. (Nazarbayev University, 2014)

The use of SERS for detection, analysis and imaging has attracted great interest in the past decade owing to its high sensitivity and molecular fingerprint specificity. There is an increasing interest in scientific ...