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Browsing NU Research Week - I by Author "Askarova, Sholpan"

Browsing NU Research Week - I by Author "Askarova, Sholpan"

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  • Cell therapeutic approaches for the treatment of experimentally induced liver fibrosis 
    Askarova, Sholpan; Umbayev, B.; Tsoy, A.; Bulanin, D.; Ongarbayeva, N.; Shalakhmetova, T. (Nazarbayev University, 2013)
    The results of our study provide evidence that HT improved animal survival and liver functions by generating an ectopic hepatic mass inside the Peyer’s patches. These observations point to the conclusion that hepatocyte ...
  • Polymer coating enhances affinity of bone marrow-derived MSCS to bone 
    Yantsen, Y.; Askarova, Sholpan; Adambekov, S.; Murata, H.; Andersen, J.; D’Souza, S.; Edington, C.; Koepsel, R.; Russell, A. (Nazarbayev University, 2013)
    The polymer coated cells were shown to be stably attached to bone fragments for at least 2 hours, confirming the bone targeting potential of the polymer. Our next step will be to test this approach in rat model of osteoporosis ...
  • Rage targeted strategies for Alzheimer`s Amyloid B peptide include blood brain barrier dysfunctions 
    Askarova, Sholpan; Tsoy, A.; Lee, J.C-M. (Nazarbayev University, 2013)
    This study demonstrated that Aβ binding to RAGE at the CECs and astrocytes surface is required for NADPH oxidase complex assembling, resulting in subsequent ROS generation and phosphorylation of cPLA2α. Therefore, understanding ...
  • Role of ROS in AB42 mediated cell surface p-selectin expression and actin polymerization 
    Tsoy, A.; Askarova, Sholpan; Shalakhmetova, T.; Umbayev, B.; Adambekov, S.; Zhumadilov, Z. (Nazarbayev University, 2013)
    The results of our study have indicated that Aβ42 induces expression of P-selectin on the surface of bEnd3 cells and promotes actin polymerization in a time dependent manner, and all these events correlate with ROS generation. ...
  • The Central Asian journal of global health to increase science productivity 
    Freese, K.; Shubnikov, E.; LaPorte, R.; Adambekov, S.; Askarova, Sholpan; Zhumadilov, Z.; Linkov, F. (Nazarbayev University, 2013)
    The Central Asian Journal of Global Health (CAJGH) is the first peer reviewed, open access journal in Central Asia (CA) aimed at those working in the areas of public health, medicine, and bioengineering. Specifically, it ...