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dc.contributor.author | Lanzafame, Massimiliano | |
dc.contributor.author | Vento, Sandro | |
dc.creator | Massimiliano, Lanzafame | |
dc.date.accessioned | 2017-12-15T03:57:32Z | |
dc.date.available | 2017-12-15T03:57:32Z | |
dc.date.issued | 2016-05-01 | |
dc.identifier | DOI:10.1016/j.jctube.2016.03.002 | |
dc.identifier.citation | Massimiliano Lanzafame, Sandro Vento, Tuberculosis-immune reconstitution inflammatory syndrome, In Journal of Clinical Tuberculosis and Other Mycobacterial Diseases, Volume 3, 2016, Pages 6-9 | en_US |
dc.identifier.issn | 24055794 | |
dc.identifier.uri | https://www.sciencedirect.com/science/article/pii/S2405579415300097 | |
dc.identifier.uri | http://nur.nu.edu.kz/handle/123456789/2920 | |
dc.description.abstract | Abstract Tuberculosis-immune reconstitution inflammatory syndrome is an excessive immune response against Mycobacterium tuberculosis that may occur in either HIV-infected or uninfected patients, during or after completion of anti-TB therapy. In HIV-infected patients it occurs after initiation of antiretroviral therapy independently from an effective suppression of HIV viremia. There are two forms of IRIS: paradoxical or unmasking. Paradoxical IRIS is characterized by recurrent, new, or worsening symptoms of a treated case. Unmasking IRIS is an antiretroviral-associated inflammatory manifestation of a subclinical infection with a hastened presentation. The pathogenesis is incompletely understood and the epidemiology partially described. No specific tests can establish or rule out the diagnosis. Treatment is based on the use of anti-tuberculosis drugs sometime with adjunctive corticosteroids. Mortality is generally low. | en_US |
dc.language.iso | en | en_US |
dc.publisher | Journal of Clinical Tuberculosis and Other Mycobacterial Diseases | en_US |
dc.relation.ispartof | Journal of Clinical Tuberculosis and Other Mycobacterial Diseases | |
dc.subject | Tuberculosis | en_US |
dc.subject | IRIS | en_US |
dc.subject | Immune reconstitution | en_US |
dc.subject | HIV | en_US |
dc.subject | Antiretrovirals | en_US |
dc.title | Tuberculosis-immune reconstitution inflammatory syndrome | en_US |
dc.type | Article | en_US |
dc.rights.license | © 2016 Published by Elsevier Ltd. | |
elsevier.identifier.doi | 10.1016/j.jctube.2016.03.002 | |
elsevier.identifier.eid | 1-s2.0-S2405579415300097 | |
elsevier.identifier.pii | S2405-5794(15)30009-7 | |
elsevier.identifier.scopusid | 84961595319 | |
elsevier.volume | 3 | |
elsevier.coverdate | 2016-05-01 | |
elsevier.coverdisplaydate | May 2016 | |
elsevier.startingpage | 6 | |
elsevier.endingpage | 9 | |
elsevier.openaccess | 1 | |
elsevier.openaccessarticle | true | |
elsevier.openarchivearticle | false | |
elsevier.openaccessuserlicense | http://creativecommons.org/licenses/by-nc-nd/4.0/ | |
elsevier.teaser | Tuberculosis-immune reconstitution inflammatory syndrome is an excessive immune response against Mycobacterium tuberculosis that may occur in either HIV-infected or uninfected patients, during or after... | |
elsevier.aggregationtype | Journal | |
workflow.import.source | science |