Isolation and enrichment of rat bone marrow mesenchymal stem cells

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Date

2016-05

Authors

Baidosova, S.
Kumasheva, V.
Kerimbayev, T.
Aleynikov, V.
Aldiyarova, N.
Ogay, Vyacheslav

Journal Title

Journal ISSN

Volume Title

Publisher

National Laboratory Astana, NAZARBAYEV UNIVERSITY

Abstract

Mesenchymal stem cells (MSCs) are a promising tool for cell therapy, because of their specific characteristics, which mimic partially those of embryonic stem cells, but with some advantages in terms of availability, expandability, transplantability and ethical implications. These cells can be isolated from the bone marrow and enriched with two mesenchymal surface markers CD54 and CD90 by immunomagnetic separation. In this regard, the purpose of this study was to isolate and enrich rat MSCs from bone marrow.

Description

Keywords

Mesenchymal stem cells, rat, bone marrow, immunomagnetic separation

Citation

S. Baidosova, V. Kumasheva, T. Kerimbayev, V. Aleynikov, N. Aldiyarova, and Vyacheslav Ogay. 2016. Isolation and enrichment of rat bone marrow mesenchymal stem cells. Abstract book. 4 th International Scientific Conference “Regenerative medicine & healthy aging”. National Laboratory Astana, Nazarbayev University. http://nur.nu.edu.kz/handle/123456789/1535

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