Astroprotective potential of extract from limonium gmelinii for stroke therapy

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Date

2016-05

Authors

Shayakhmetov, Y.
Tsoy, A.
Zhussupova, G.
Askarova, Sh.

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Abstract

It's known that proinflammatory cytokines, such asTNF-a, produced by injured neurons and infiltrated leukocytes, involved in every aspect of stroke. Cytokines promote activation of astroglia, induce oxidative stress thereby exacerbating brain tissue damage. There is a number of data indicating that polyphenols can provide protection against neurodegenerative changes. It has been reported previously, that reach with polyphenols extract of Limonium gmelinii exerts a wide range of therapeutic actions. Here, we aimed to study antioxidant and anti-inflammatory potential of L. gmelinii under exposure of TNF-a in vitro.

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Keywords

Limonium gmelinii, stroke therapy

Citation

Shayakhmetov Y., Tsoy A., Zhussupova G., and Askarova Sh. 2016. Astroprotective potential of extract from limonium gmelinii for stroke therapy. Abstract book. 4 th International Scientific Conference “Regenerative medicine & healthy aging”. National Laboratory Astana, Nazarbayev University. http://nur.nu.edu.kz/handle/123456789/1507

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