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Browsing 13.Materials of Forums, Conferences and Projects by Author

Browsing 13.Materials of Forums, Conferences and Projects by Author "Shustov, A. V."

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Development of a recombinant foot -and-mouth disease vaccine

Kalieva, M. Zh.; Shagyrova, Zh. S.; Voykov, M.; Ramanculov, E. M.; Shustov, A. V. (Nazarbayev University, 2014)

Foot-and-mouth disease (FMD) is important disease of cloven-foot animals including cows and swine. Although annual vaccination against the FMD is mandated in regions of South Kazakhstan, outbreaks of the disease are ...
Development of a technology for expression of recombinant human erythropoietin in cultured mammalian cells using alphavirus expression system

Evtyhova, E. B.; Voykov, M.; Ramanculov, E. M.; Shustov, A. V. (Nazarbayev University, 2014)

Currently there are no industrial eukaryotic expression systems other than transient expression from plasmids or expression from genes integrated into host genome. Both approaches (use of eukaryotic plasmids or chromosomal ...
Development of non-integrative autonomously replicating vectors for epigenetic reprogramming of somatic cells

Shustov, A. V.; Baltabekova, A.Zh.; Evtyhova, L.B.; Ramankulov, Ye.M. (Nazarbayev University, 2013)

The idea of the project is to utilize the genome of well-described alphavirus VEE as vector for delivery and expression of the human pluripotency factors used for epigenetic reprogramming of somatic cells, namely Nanog, ...
Split core technology allows efficient production of virus-like particles presenting a receptor-contacting epitope of human IgE

Baltabekova, A. Zh.; Shagyrova, Zh. S.; Voykov, M.; Ramanculov, E. M.; Shustov, A. V. (Nazarbayev University, 2014)

Immunoglobulin E (IgE) plays a central role in type I hypersensitivity including allergy and asthma. Novel treatment strategy envisages development of a therapeutic vaccine designed to elicit autologous blocking antibodies ...