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Browsing 13.Materials of Forums, Conferences and Projects by Author "Adarichev, V. A."

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Browsing 13.Materials of Forums, Conferences and Projects by Author "Adarichev, V. A."

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  • Design and development of multivalent peptide vaccine candidate against influenza a virus 
    Chinybayeva, A. K.; Kabdullina, A.; Soltabayeva, A.; Myngbay, A.; Adarichev, V. A.; Alibek, K. (Nazarbayev University, 2013)
    Influenza virus is a major pathogen with global spread which infects birds and mammals, including humans. The virus is constantly changing, thus influenza stays in the centre of vaccine research. Effective vaccine should ...
  • Genetic homongeneity and major histocompatibility complex haplotyping of white mice 
    Sydykova, K.; Sadykov, M.; Zhailauova, A.; Adilbayeva, A.; Myngbay, A.; Adarichev, V. A. (Nazarbayev University, 2014)
    Inbred murine strains are generated to insure genetic homogeneity and uniqueness and define immune characteristics, like major histocompatibility complex (MHC) haplotype, of the experimental model. Maintaining of the ...
  • Molecular mimicry of brucella melitensis epitopes in mouse and human arthritis 
    Bexeitov, Y. K.; Ramez, M; Forde, T. S.; Adarichev, V. A. (Nazarbayev University, 2014)
    Brucellosis is one of the most frequent zoonosis worldwide. Infection is transferable to humans, where brucellosis is associated with high incidence of osteoarticular disease including osteomyelitis, arthritis and ...
  • New arthritic pannus-specific protein promotes fibroblast motility and polarization 
    Adilbayeva, A.; Myngbay, A.; Adarichev, V. A. (Nazarbayev University, 2014)
    Rheumatoid arthritis (RA) is chronic inflammatory disease characterized by the development of hypercellular pannus tissue in the affected joints of patients. Pannus invasiveness and activation correlates with stronger ...
  • New serum biomarker for rheumatoid arthritis 
    Myngbay, A.; Adilbayeva, A.; Adarichev, V. A. (Nazarbayev University, 2014)
    Development of hypercellular invasive pannus tissue within synovial joints is a hallmark of Rheumatoid Arthritis (RA). Pannus produces proteases that damage bone and cartilage. Non-invasive monitoring of pannus activity ...
  • Protective effect of peptide vaccination in murine infection with influenza virus 
    Myngbay, A.; Adilbayeva, A.; Sadykov, M.; Zhailauova, A.; Adarichev, V. A.; Alibek, K. (Nazarbayev University, 2014)
    Vaccination is a major tool to protect people from seasonal infections of different strains of influenza virus that presently infects millions of individuals worldwide. Virus genome is highly polymorphic, and universal ...
  • Transcriptome of congenic mice with transient inflammatory arthritis: resque of C5 complement deficiency 
    Adarichev, V. A.; Sarkar, S.; Kalamov, N.; Brucker, J.; Forde, T. S.; Shekhani, M.T.; Lyons, B. (Nazarbayev University, 2013)
    We found that Pgis2-congenic mice that carry genetically-deficient copy of C5(Hc) complement component were susceptible to collagen antibody-induced arthritis while inflammation was transient. Using differential gene ...