Browsing Articles by Subject "Antiviral drugs"

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Simian Virus 40 Large T Antigen as a Model to Test the Efficacy of Flouroquinolones against Viral Helicases

Siddiqui, Sammer; Anwar, Muhammad F.; Naeem, Sadaf; Abidi, Syed Hani; Zarina, Shamshad; Ali, Syed (Biomedical Informatics, 2018-02-28)

Simian virus 40 large T-antigen (SV40 LT-Ag) is a 708 amino acid nuclear phosphoprotein. Among many functions of LT-Ag is its ability to perform as an ATPase-helicase, catalyzing the unwinding of viral genome during ...