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Browsing Articles by Subject "colorectal cancer"

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Biomarkers and signaling pathways of colorectal cancer stem cells

Abetov, Danysh; Mustapova, Zhanar; Saliev, Timur; Bulanin, Denis (Tumor Biology, 2015-03-01)

The progression of colorectal cancer is commonly characterized by accumulation of genetic or epigenetic abnormalities, altering regulation of gene expression as well as normal protein structures and functions. Nonetheless, ...
Establishment and Characterization of 5-Fluorouracil-Resistant Human Colorectal Cancer Stem-Like Cells: Tumor Dynamics under Selection Pressure

Francipane, M. G.; Bulanin, Denis; Lagasse, E. (MDPI, 2019-04-12)

5-Fluorouracil (5-FU) remains the gold standard of first-line treatment for colorectal cancer (CRC). Although it may initially debulk the tumor mass, relapses frequently occur, indicating the existence of cancer cells that ...
KCNB1 GENE POLYMORPHISMS AND RELATED INDEL AS PREDICTOR BIOMARKERS OF TREATMENT RESPONSE FOR COLORECTAL CANCER – TOWARD A PERSONALIZED MEDICINE

Barbirou, Mouadh; Sghaier, Ikram; Bedoui, Sinda; Ben Abderrazek, Rahma; Kraiem, Hazar; Farah, Azer; Hassiki, Rym; Mokrani, Amina; Mezlini, Amel; Almawi, Wassim Y; Loueslati-Yacoubi, Besma; Bouhaouala-Zahar, Balkiss (International Society of Oncology and BioMarkers, 2020-06)

The KCNB1 gene variants were differentially associated with cancers. However, their association with colorectal cancer has not yet been explored. We investigated the contribution of the KCNB1 gene variants rs3331, rs1051295, ...
Late Diagnosis of Post-partum Colorectal Cancer in a Young Kazakh Woman

Dauyey, Kaisar; Jumadilova, Dinara (Ivy Union Publishing, 2020)

Introduction: Colorectal cancer (CRC) is generally expected among population above 60 years of age and rarely occurs in younger age groups. Its occurrence in young individuals is sporadic and has poor prognosis. Presentation ...