Browsing Articles by Author "95c6932c-427a-4351-8401-fe1c27d5217b"

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AXL RECEPTOR IN CANCER METASTASIS AND DRUG RESISTANCE: WHEN NORMAL FUNCTIONS GO ASKEW

Auyez, Almira; Sayan, A. Emre; Kriajevska, Marina; Tulchinsky, Eugene (MDPI, 2021-09-28)

The TAM proteins TYRO3, AXL, and MER are receptor tyrosine kinases implicated in the clearance of apoptotic debris and negative regulation of innate immune responses. AXL contributes to immunosuppression by terminating the ...
ZEB1 and IL-6/11-STAT3 signalling cooperate to define invasive potential of pancreatic cancer cells via differential regulation of the expression of S100 proteins

Al-Ismaeel, Qais; Neal, Christopher P.; Al-Mahmoodi, Hanaa; Almutairi, Zamzam; Al-Shamarti, Ibtihal; Straatman, Kees; Jaunbocus, Nabil; Irvine, Andrew; Issa, Eyad; Moreman, Catherine; Dennison, Ashley R.; Sayan, A. Emre; McDearmid, Jonathan; Greaves, Peter; Tulchinsky, Eugene; Kriajevska, Marina (NATURE PUBLISHING GROUP, 2019-07-02)

Background S100 proteins have been implicated in various aspects of cancer, including epithelial-mesenchymal transitions (EMT), invasion and metastasis, and also in inflammatory disorders. Here we examined the impact of ...