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Browsing Articles by Author "6a360225-c34c-4335-9671-74e17e9e0962"

Now showing items 1-7 of 7

Acceleration of Skin Wound-Healing Reactions by Autologous Micrograft Tissue Suspension

Jimi, Shiro; Takagi, Satoshi; De Francesco, Francesco; Miyazaki, Motoyasu; Saparov, Arman (MDPI, 2020-06)

Background and objectives: Skin grafting is a method usually used in reconstructive surgery to accelerate skin regeneration. This method results frequently in unexpected scar formations. We previously showed that cutaneous ...
COLLAGEN-DERIVED DIPEPTIDE PRO-HYP ADMINISTRATION ACCELERATES MUSCLE REGENERATIVE HEALING ACCOMPANIED BY LESS SCARRING AFTER WOUNDING ON THE ABDOMINAL WALL IN MICE

Jimi, Shiro; Koizumi, Seiko; Miyazaki, Motoyasu; Saparov, Arman (Scientific Reports, 2021)

Collagens act as cellular scaffolds in extracellular matrixes, and their breakdown products may also have important biological functions. We hypothesize that collagen dipeptide Pro-Hyp induces favorable healing activities ...
EDITORIAL: CELLULAR AND MOLECULAR MECHANISMS AT THE PROLIFERATION STAGE IN WOUND HEALING: FROM SCARRING TO TISSUE REGENERATION

Jimi, Shiro; Saparov, Arman; Takagi, Satoshi (Front. Cell Dev. Biol., 2021-02-19)

Wound healing is a complex physiological reaction in our body to tissue injury that can lead to the impairment of the original organ functions depending on the area of tissue injury. Many cell types participate in the wound ...
IMMUNOLOGY OF ACUTE AND CHRONIC WOUND HEALING

Raziyeva, Kamila; Kim, Yevgeniy; Zharkinbekov, Zharylkasyn; Kassymbek, Kuat; Jimi, Shiro; Saparov, Arman (MDPI AG, 2021-05-08)

Skin wounds greatly affect the global healthcare system, creating a substantial burden on the economy and society. Moreover, the situation is exacerbated by low healing rates, which in fact are overestimated in reports. ...
A NOVEL AUTOLOGOUS MICROGRAFTS TECHNOLOGY IN COMBINATION WITH NEGATIVE PRESSURE WOUND THERAPY (NPWT) FOR QUICK GRANULATION TISSUE FORMATION IN CHRONIC/REFRACTORY ULCER

Takagi, Satoshi; Oyama, Takuto; Jimi, Shiro; Saparov, Arman; Ohjimi, Hiroyuki (MDPI, 2020-11-25)

Negative pressure wound therapy (NPWT) has been commonly used over the years for a wide range of chronic/refractory lesions. Alternatively, autologous micrografting technology is recently becoming a powerful modality for ...
RECENT ADVANCES IN THE CONTROLLED RELEASE OF GROWTH FACTORS AND CYTOKINES FOR IMPROVING CUTANEOUS WOUND HEALING

Nurkesh, Ayan; Jaguparov, Alexandr; Jimi, Shiro; Saparov, Arman (Frontiers Media, 2020-07)

Bioengineered materials are widely utilized due to their biocompatibility and degradability, as well as their moisturizing and antibacterial properties. One field of their application in medicine is to treat wounds by ...
SEQUENTIAL DELIVERY OF CRYOGEL RELEASED GROWTH FACTORS AND CYTOKINES ACCELERATES WOUND HEALING AND IMPROVES TISSUE REGENERATION

Jimi, Shiro; Jaguparov, Alexandr; Nurkesh, Ayan; Sultankulov, Bolat; Saparov, Arman (Frontiers in Bioengineering and Biotechnology, 2020-04)

Growth factors and cytokines that are secreted by cells play a crucial role in the complex physiological reaction to tissue injury. The ability to spatially and temporally control their actions to maximize regenerative ...