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Browsing School of Medicine by Subject "cancer"

Browsing School of Medicine by Subject "cancer"

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  • Anticancer activity of metformin: a systematic review of the literature 
    Aljofan, Mohamad; Riethmacher, Dieter (FUTURE SCI LTD, 2019-08)
    BACKGROUND: The anticancer activity of metformin has been confirmed against several cancer types in vitro and in vivo. However, the underlying mechanisms of metformin in the treatment of cancer are not fully understood. ...
  • Application of molecular genotyping to determine prevalence of HPV strains in Pap smears of Kazakhstan women 
    Niyazmetova, Luiza; Aimagambetova, Gulzhanat; Stambekova, Nazigul; Abugalieva, Zaurech; Seksembayeva, Korlukain; Syed, Ali; Azizan, Azliyati (International Journal of Infectious Diseases, 2016-11-20)
    Objectives: Human papillomavirus is themain causative agent for cervical cancer. However, few data are available about HPV prevalence in Kazakhstan. The aims of this study were to genotype HPV DNA in Pap smear samples of ...
  • Human Papillomavirus Infection and Cervical Cancer: Epidemiology, Screening, and Vaccination-Review of Current Perspectives 
    Chan, Chee-Kai; Aimagambetova, Gulzhanat; Ukybassova, Talshyn; Kongrtay, Kuralay; Azizan, Azliyati (Hindawi, 2019-10)
    Viral infections contribute as a cause of 15–20% of all human cancers. Infection by oncogenic viruses can promote different stages of carcinogenesis. Among many types of HPV, around 15 are linked to cancer. In spite of ...
  • Knowledge, attitudes and practices among Kazakhstan’s physicians towards cervical cancer and Human Papilloma Virus 
    Babi, Aisha (Nazarbayev University School of Medicine, 2019)
    Cervical cancer is a high burden disease worldwide that often results from the infection by the Human Papilloma Virus (HPV). It is one of the most preventable cancers, as vaccines against HPV that can prevent more than 90% ...
  • LUNG DEVELOPMENT, REPAIR AND CANCER: A STUDY ON THE ROLE OF MMP20 GENE IN ADENOCARCINOMA 
    Mok, Pooi Ling; Anandasayanam, Arun Neela Kumar; Oscar David, Hernandez Maradiaga; Tong, Jiabei; Farhana, Aisha; Khan, Mohammed Safwan Ali; Sivaprakasam, Gothai; Koh, Avin Ee-Hwan; Alzahrani, Badr (Public Library of Science, 2021-04-29)
    Multiple matrix metalloproteinases have significant roles in tissue organization during lung development, and repair. Imbalance of proteinases may lead to chronic inflammation, changes in tissue structure, and are also ...
  • Metformin: A stroke of luck 
    Aljofan, Mohamad; Gaipov, Abduzhappar (MODESTUM LTD, 2019-03)
    Metformin is an oral glucose-lowering drug that has been widely used for more than half a century. Both the American Diabetes Association and the European Association for the study of Diabetes recommend metformin as the ...
  • Novel Small Molecule Inhibitors of Cancer Stem Cell Signaling Pathways 
    Abetov, Danysh; Mustapova, Zhanar; Saliev, Timur; Bulanin, Denis; Batyrbekov, Kanat; Gilman, Charles P. (Stem Cell Reviews and Reports, 2015-12-01)
    The main aim of oncologists worldwide is to understand and then intervene in the primary tumor initiation and propagation mechanisms. This is essential to allow targeted elimination of cancer cells without altering normal ...
  • The Role of Pathologist in Quality Assurance of Cancer Biomarking 
    Jasani, Bharat (2015-09)
    Reflections on the past:  Previous home and institution  Path to a clinical academic career in pathology  Role of a pathologist in diagnostic medicine Cancer biomarking: Role in diagnostic pathology Quality ...
  • Tumor antigens as proteogenomic biomarkers in invasive ductal carcinomas 
    Olsen, Lars Rønn; Campos, Benito; Winther, Ole; Sgroi, Dennis C.; Karger, Barry L.; Brusic, Vladimir (BMC Medical Genomics, 2014-12-08)
    Background: The majority of genetic biomarkers for human cancers are defined by statistical screening of high-throughput genomics data. While a large number of genetic biomarkers have been proposed for diagnostic and ...