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Browsing School of Medicine by Title

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  • SALIVARY MICROBIOME IN PEDIATRIC AND ADULT CELIAC DISEASE 
    Poddighe, Dimitri; Kushugulova, Almagul R. (Front. Cell. Infect. Microbiol., 2021-02-17)
    The human salivary microbiota includes hundreds of bacterial species. Alterations in gut microbiota have been explored in Celiac Disease (CD), but fewer studies investigated the characteristics of salivary microbiome in ...
  • SARS-COV-2 PCR-POSITIVE AND PCR-NEGATIVE CASES OF PNEUMONIA ADMITTED TO THE HOSPITAL DURING THE PEAK OF COVID-19 PANDEMIC: ANALYSIS OF IN-HOSPITAL AND POSTHOSPITAL MORTALITY 
    Gaipov, Abduzhappar; Gusmanov, Arnur; Abbay, Anara; Sakko, Yesbolat; Issanov, Alpamys; Kadyrzhanuly, Kainar; Yermakhanova, Zhanar; Aliyeva, Lazzat; Kashkynbayev, Ardak; Moldaliyev, Iklas; Crape, Byron; Sarria-Santamera, Antonio (BMC Infectious Diseases, 2021-05)
    During the spike of COVID-19 pandemic in Kazakhstan (June-2020), multiple SARS-CoV-2 PCR-test negative pneumonia cases with higher mortality were reported by media. We aimed to study the epidemiologic characteristics of ...
  • SARS-COV-2 PCR-POSITIVE AND PCR-NEGATIVE CASES OF PNEUMONIA ADMITTED TO THE HOSPITAL DURING THE PEAK OF COVID-19 PANDEMIC: ANALYSIS OF IN-HOSPITAL AND POSTHOSPITAL MORTALITY 
    Gaipov, Abduzhappar; Gusmanov, Arnur; Abbay, Anara; Sakko, Yesbolat; Issanov, Alpamys; Kadyrzhanuly, Kainar; Yermakhanova, Zhanar; Aliyeva, Lazzat; Kashkynbayev, Ardak; Moldaliyev, Iklas; Crape, Byron; Sarria-Santamera, Antonio (BioMed Central Ltd, 2021-05-20)
    Background: During the spike of COVID-19 pandemic in Kazakhstan (June-2020), multiple SARS-CoV-2 PCR-test negative pneumonia cases with higher mortality were reported by media. We aimed to study the epidemiologic characteristics ...
  • Scatter Factor/Hepatocyte Growth Factor and Its Receptor, the c-met Tyrosine Kinase, Can Mediate a Signal Exchange between Mesenchyme and Epithelia during Mouse Development 
    Sonnenberg-Riethmacher, Eva (The Rockefeller University Press, 1993)
    Scatter factor/hepatocyte growth factor (SF/HGF) has potent motogenic, mitogenic, and morphogenetic activities on epithelial cells in vitro. The cell surface receptor for this factor was recently identified: it is the ...
  • SCOPE OF NURSING PRACTICE AS PERCEIVED BY NURSES WORKING IN SAUDI ARABIA 
    Aljohani, Khalid A.; Alamri, Majed S.; AL-Dossary, Reem; Albaqawi, Hamdan; Hosis, Khaled Al; Aljohani, Mohammed S.; Almadani, Noura; Alrasheadi, Bader; Falatah, Rawaih; Almazan, Joseph; Alharbi, Jalal (International Journal of Environmental Research and Public Health, 2022)
    The absence of scope of practice guidelines may lead to role ambiguity and legal conse quences in nursing practice. This study measures the scope of practice of nurses in Saudi Arabia. The study utilized a descriptive ...
  • Sebaceous lipids are essential for water repulsion, protection against UVB-induced apoptosis and ocular integrity in mice 
    Dahlhoff, Maik; Camera, Emanuela; Schäfer, Matthias; Emrich, Daniela; Riethmacher, Dieter; Foster, April; Paus, Ralf; Schneider, Marlon R. (Development (Cambridge), 2016-05-15)
    Sebocytes, which are characterized by lipid accumulation that leads to cell disruption, can be found in hair follicle-associated sebaceous glands (SGs) or in free SGs such as the Meibomian glands in the eyelids. Because ...
  • SEQUENTIAL DELIVERY OF CRYOGEL RELEASED GROWTH FACTORS AND CYTOKINES ACCELERATES WOUND HEALING AND IMPROVES TISSUE REGENERATION 
    Jimi, Shiro; Jaguparov, Alexandr; Nurkesh, Ayan; Sultankulov, Bolat; Saparov, Arman (Frontiers in Bioengineering and Biotechnology, 2020-04)
    Growth factors and cytokines that are secreted by cells play a crucial role in the complex physiological reaction to tissue injury. The ability to spatially and temporally control their actions to maximize regenerative ...
  • SEROPOSITIVITY OF SARS-COV-2 IN THE POPULATION OF KAZAKHSTAN: A NATIONWIDE LABORATORY-BASED SURVEILLANCE 
    Semenova, Yuliya; Kalmatayeva, Zhanna; Oshibayeva, Ainash; Mamyrbekova, Saltanat; Kudirbekova, Aynura; Nurbakyt, Ardak; Baizhaxynova, Ardak; Colet, Paolo; Glushkova, Natalya; Ivankov, Alexandr; Sarria-Santamera, Antonio (International Journal of Environmental Research and Public Health, 2022)
    The data on seroprevalence of anti-SARS-CoV-2 antibodies in Kazakhstani population are non-existent, but are needed for planning of public health interventions targeted to COVID-19 containment. The aim of the study was ...
  • SHORT-TERM EFFECT OF LDL-APHERESIS ON LIPID PROFILE OF PATIENTS WITH NEPHROTIC AND NON-NEPHROTIC HYPERLIPIDEMIA: A COMPARATIVE STUDY 
    Gaipov, Abduzhappar; Nogaibayeva, Assem; Turebekov, Zaiyrkhan; Zharmukhanbet, Lyazzat; Orazbayev, Gani; Malykh, Dmitriy; Kim, Natalya; Abbay, Anara; Tuganbekova, Saltanat; Aljofan, Mohamad; Bekishev, Bolat (Electronic Journal of General Medicine, 2021-04-27)
    Background: Persistent hyperlipidemia is a major cause of cardiovascular morbidity in patients with nephrotic and non-nephrotic patients. Low-density lipoprotein-apheresis (LDL-apheresis) was shown to rapidly remove lipid ...
  • Simian Virus 40 Large T Antigen as a Model to Test the Efficacy of Flouroquinolones against Viral Helicases 
    Siddiqui, Sammer; Anwar, Muhammad F.; Naeem, Sadaf; Abidi, Syed Hani; Zarina, Shamshad; Ali, Syed (Biomedical Informatics, 2018-02-28)
    Simian virus 40 large T-antigen (SV40 LT-Ag) is a 708 amino acid nuclear phosphoprotein. Among many functions of LT-Ag is its ability to perform as an ATPase-helicase, catalyzing the unwinding of viral genome during ...
  • SÍNDROME DE ABSTINÊNCIA DE ROPIVACAÍNA: RELATO DE CASO 
    Viderman, Dmitriy; Portnyagin, Ivan; la Fleur, Philip; Bilotta, Federico (Elsevier, 2020-02-19)
    Justificativa e objetivos:A ropivacaína é um anestésico local de ac ̧ão prolongada indicado emuma ampla variedade de cirurgias. Toxicidade sistêmica tem sido relatada após o uso de dosealta de ropivacaína ou administrac ...
  • SLEEP, BRAIN VASCULAR HEALTH AND AGEING 
    Mahalakshmi, Arehally M.; Ray, Bipul; Tuladhar, Sunanda; Bhat, Abid; Bishir, Muhammed; Bolla, Srinivasa Rao; Yang, Jian; Essa, Musthafa Mohamed; Chidambaram, Saravana Babu; Guillemin, Gilles J.; Sakharkar, Meena Kishore (GeroScience, 2020-08-03)
    Sleep maintains the function of the entire body through homeostasis. Chronic sleep deprivation (CSD) is a prime health concern in the modern world. Previous reports have shown that CSD has profound negative effects on ...
  • Socio-demographic factors associated with malnutrition of children under-5 years of age in Kazakhstan 
    Sakko, Yesbolat (Nazarbayev University School of Medicine, 2019)
    The objective of this study was to determine potential risk factors associated with child malnutrition status. It investigates key predictors of nutrition status such as age, gender, region of origin, nationality, wealth, ...
  • THE SOCIOECONOMIC GRADIENT OF ALCOHOL USE: AN ANALYSIS OF NATIONALLY REPRESENTATIVE SURVEY DATA FROM 55 LOW-INCOME AND MIDDLE-INCOME COUNTRIES 
    Xu, Yuanwei; Geldsetzer, Pascal; Manne-Goehler, Jen; Theilmann, Michaela; Marcus, Maja-E; Zhumadilov, Zhaxybay; Quesnel-Crooks, Sarah; Mwalim, Omar; Moghaddam, Sahar Saeedi; Koolaji, Sogol; Karki, Khem B; Farzadfar, Farshad; Ebrahimi, Narges; Damasceno, Albertino; Aryal, Krishna K; Agoudavi, Kokou; Atun, Rifat; Bärnighausen, Till; Davies, Justine; Jaacks, Lindsay M; Vollmer, Sebastian; Probst, Charlotte (The Lancet Global Health, 2022)
    Background Alcohol is a leading risk factor for over 200 conditions and an important contributor to socioeconomic health inequalities. However, little is known about the associations between individuals’ socioeconomic ...
  • Spontaneous abortion in Astana: Associated factors, 2015-2017 
    Zhanseitova, Akzhan (Nazarbayev University School of Medicine, 2018-05)
    Background Spontaneous abortion is the most common adverse pregnancy outcome. That is a great challenge for any healthcare facility and population health. The present study is aimed to investigate the associated risk ...
  • The Spread of HIV in Pakistan: Bridging of the Epidemic between Populations 
    Khanani, Muhammad R.; Somani, Mehreen; Rehmani, Sadiq S.; Veras, Nazle M. C.; Ali, Syed (Public Library of Science, 2011-07-25)
    In the last two decades, ‘concentrated epidemics’ of human immunodeficiency virus (HIV) have established in several high risk groups in Pakistan, including Injecting Drug Users (IDUs) and among men who have sex with men ...
  • STAPHYLOCOCCUS AUREUS INFECTION AND PERSISTENCE IN CHRONIC RHINOSINUSITIS: FOCUS ON LEUKOCIDIN ED 
    Poddighe, Dimitri; Vangelista, Luca (MDPI, 2020-10-28)
    Chronic rhinosinusitis (CRS) is thought to be a multifactorial disease that includes a direct involvement of bacteria that trigger inflammation and contribute to CRS pathogenesis. Staphylococcus aureus infection and ...
  • Stem Cells Therapy in General Medicine 
    Gaipov, Abduzhappar; Myngbay, Askhat (2018-01)
    Regenerative medicine is much of intense interest among scientists and clinicians. This is a comparatively new field and needs further developments in use. To date, more than 355K in PubMed and almost 3M in Google Scholar, ...
  • STIGMA TOWARDS HEALTH CARE PROVIDERS TAKING CARE OF COVID-19 PATIENTS: A MULTI-COUNTRY STUDY 
    Nashwan, Abdulqadir J.; Valdez, Glenn Ford D.; AL-Fayyadh, Sadeq; Al-Najjar, Hani; Elamir, Hossam; Barakat, Muna; Almazan, Joseph U.; Jahlan, Ibtesam O.; Alabdulaziz, Hawa; Omar, Nabil E.; Alawneh, Fade; Priastana, I. Ketut Andika; Alhanaf, Aiman; Abu-Hussein, Bilal; Al-Shammari, Malik; Shaban, Marwa M.; Shaban, Mostafa; AL-Hadrawi, Hayder; Al-Jubouri, Mohammed B.; Jaafar, Sabah A.; Hussein, Shaymaa M.; Nashwan, Ayat J.; Alharahsheh, Mohammed A.; Kader, Nisha; Alabdulla, Majid; Nazarene, Ananth; Yassin, Mohamed A.; Villar, Ralph C. (Heliyon, 2022)
    Background: Health care providers (HCPs) have always been a common target of stigmatization during widespread infections and COVID-19 is not an exception. Aim: This study aims to investigate the prevalence of stigmatization ...
  • STIMULI-RESPONSIVE POLYMERS FOR TRANSDERMAL, TRANSMUCOSAL AND OCULAR DRUG DELIVERY 
    Berillo, Dmitriy; Zharkinbekov, Zharylkasyn; Kim, Yevgeniy; Raziyeva, Kamila; Temirkhanova, Kamila; Saparov, Arman (MDPI, 2021-12-01)
    Despite their conventional and widespread use, oral and intravenous routes of drug administration face several limitations. In particular, orally administered drugs undergo enzymatic degradation in the gastrointestinal ...