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Browsing School of Medicine by Title

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  • SEQUENTIAL DELIVERY OF CRYOGEL RELEASED GROWTH FACTORS AND CYTOKINES ACCELERATES WOUND HEALING AND IMPROVES TISSUE REGENERATION 
    Jimi, Shiro; Jaguparov, Alexandr; Nurkesh, Ayan; Sultankulov, Bolat; Saparov, Arman (Frontiers in Bioengineering and Biotechnology, 2020-04)
    Growth factors and cytokines that are secreted by cells play a crucial role in the complex physiological reaction to tissue injury. The ability to spatially and temporally control their actions to maximize regenerative ...
  • SEROPOSITIVITY OF SARS-COV-2 IN THE POPULATION OF KAZAKHSTAN: A NATIONWIDE LABORATORY-BASED SURVEILLANCE 
    Semenova, Yuliya; Kalmatayeva, Zhanna; Oshibayeva, Ainash; Mamyrbekova, Saltanat; Kudirbekova, Aynura; Nurbakyt, Ardak; Baizhaxynova, Ardak; Colet, Paolo; Glushkova, Natalya; Ivankov, Alexandr; Sarria-Santamera, Antonio (International Journal of Environmental Research and Public Health, 2022)
    The data on seroprevalence of anti-SARS-CoV-2 antibodies in Kazakhstani population are non-existent, but are needed for planning of public health interventions targeted to COVID-19 containment. The aim of the study was ...
  • SHORT-TERM EFFECT OF LDL-APHERESIS ON LIPID PROFILE OF PATIENTS WITH NEPHROTIC AND NON-NEPHROTIC HYPERLIPIDEMIA: A COMPARATIVE STUDY 
    Gaipov, Abduzhappar; Nogaibayeva, Assem; Turebekov, Zaiyrkhan; Zharmukhanbet, Lyazzat; Orazbayev, Gani; Malykh, Dmitriy; Kim, Natalya; Abbay, Anara; Tuganbekova, Saltanat; Aljofan, Mohamad; Bekishev, Bolat (Electronic Journal of General Medicine, 2021-04-27)
    Background: Persistent hyperlipidemia is a major cause of cardiovascular morbidity in patients with nephrotic and non-nephrotic patients. Low-density lipoprotein-apheresis (LDL-apheresis) was shown to rapidly remove lipid ...
  • Simian Virus 40 Large T Antigen as a Model to Test the Efficacy of Flouroquinolones against Viral Helicases 
    Siddiqui, Sammer; Anwar, Muhammad F.; Naeem, Sadaf; Abidi, Syed Hani; Zarina, Shamshad; Ali, Syed (Biomedical Informatics, 2018-02-28)
    Simian virus 40 large T-antigen (SV40 LT-Ag) is a 708 amino acid nuclear phosphoprotein. Among many functions of LT-Ag is its ability to perform as an ATPase-helicase, catalyzing the unwinding of viral genome during ...
  • SÍNDROME DE ABSTINÊNCIA DE ROPIVACAÍNA: RELATO DE CASO 
    Viderman, Dmitriy; Portnyagin, Ivan; la Fleur, Philip; Bilotta, Federico (Elsevier, 2020-02-19)
    Justificativa e objetivos:A ropivacaína é um anestésico local de ac ̧ão prolongada indicado emuma ampla variedade de cirurgias. Toxicidade sistêmica tem sido relatada após o uso de dosealta de ropivacaína ou administrac ...
  • SLEEP, BRAIN VASCULAR HEALTH AND AGEING 
    Mahalakshmi, Arehally M.; Ray, Bipul; Tuladhar, Sunanda; Bhat, Abid; Bishir, Muhammed; Bolla, Srinivasa Rao; Yang, Jian; Essa, Musthafa Mohamed; Chidambaram, Saravana Babu; Guillemin, Gilles J.; Sakharkar, Meena Kishore (GeroScience, 2020-08-03)
    Sleep maintains the function of the entire body through homeostasis. Chronic sleep deprivation (CSD) is a prime health concern in the modern world. Previous reports have shown that CSD has profound negative effects on ...
  • Socio-demographic factors associated with malnutrition of children under-5 years of age in Kazakhstan 
    Sakko, Yesbolat (Nazarbayev University School of Medicine, 2019)
    The objective of this study was to determine potential risk factors associated with child malnutrition status. It investigates key predictors of nutrition status such as age, gender, region of origin, nationality, wealth, ...
  • THE SOCIOECONOMIC GRADIENT OF ALCOHOL USE: AN ANALYSIS OF NATIONALLY REPRESENTATIVE SURVEY DATA FROM 55 LOW-INCOME AND MIDDLE-INCOME COUNTRIES 
    Xu, Yuanwei; Geldsetzer, Pascal; Manne-Goehler, Jen; Theilmann, Michaela; Marcus, Maja-E; Zhumadilov, Zhaxybay; Quesnel-Crooks, Sarah; Mwalim, Omar; Moghaddam, Sahar Saeedi; Koolaji, Sogol; Karki, Khem B; Farzadfar, Farshad; Ebrahimi, Narges; Damasceno, Albertino; Aryal, Krishna K; Agoudavi, Kokou; Atun, Rifat; Bärnighausen, Till; Davies, Justine; Jaacks, Lindsay M; Vollmer, Sebastian; Probst, Charlotte (The Lancet Global Health, 2022)
    Background Alcohol is a leading risk factor for over 200 conditions and an important contributor to socioeconomic health inequalities. However, little is known about the associations between individuals’ socioeconomic ...
  • Spontaneous abortion in Astana: Associated factors, 2015-2017 
    Zhanseitova, Akzhan (Nazarbayev University School of Medicine, 2018-05)
    Background Spontaneous abortion is the most common adverse pregnancy outcome. That is a great challenge for any healthcare facility and population health. The present study is aimed to investigate the associated risk ...
  • The Spread of HIV in Pakistan: Bridging of the Epidemic between Populations 
    Khanani, Muhammad R.; Somani, Mehreen; Rehmani, Sadiq S.; Veras, Nazle M. C.; Ali, Syed (Public Library of Science, 2011-07-25)
    In the last two decades, ‘concentrated epidemics’ of human immunodeficiency virus (HIV) have established in several high risk groups in Pakistan, including Injecting Drug Users (IDUs) and among men who have sex with men ...
  • STAPHYLOCOCCUS AUREUS INFECTION AND PERSISTENCE IN CHRONIC RHINOSINUSITIS: FOCUS ON LEUKOCIDIN ED 
    Poddighe, Dimitri; Vangelista, Luca (MDPI, 2020-10-28)
    Chronic rhinosinusitis (CRS) is thought to be a multifactorial disease that includes a direct involvement of bacteria that trigger inflammation and contribute to CRS pathogenesis. Staphylococcus aureus infection and ...
  • Stem Cells Therapy in General Medicine 
    Gaipov, Abduzhappar; Myngbay, Askhat (2018-01)
    Regenerative medicine is much of intense interest among scientists and clinicians. This is a comparatively new field and needs further developments in use. To date, more than 355K in PubMed and almost 3M in Google Scholar, ...
  • STIGMA TOWARDS HEALTH CARE PROVIDERS TAKING CARE OF COVID-19 PATIENTS: A MULTI-COUNTRY STUDY 
    Nashwan, Abdulqadir J.; Valdez, Glenn Ford D.; AL-Fayyadh, Sadeq; Al-Najjar, Hani; Elamir, Hossam; Barakat, Muna; Almazan, Joseph U.; Jahlan, Ibtesam O.; Alabdulaziz, Hawa; Omar, Nabil E.; Alawneh, Fade; Priastana, I. Ketut Andika; Alhanaf, Aiman; Abu-Hussein, Bilal; Al-Shammari, Malik; Shaban, Marwa M.; Shaban, Mostafa; AL-Hadrawi, Hayder; Al-Jubouri, Mohammed B.; Jaafar, Sabah A.; Hussein, Shaymaa M.; Nashwan, Ayat J.; Alharahsheh, Mohammed A.; Kader, Nisha; Alabdulla, Majid; Nazarene, Ananth; Yassin, Mohamed A.; Villar, Ralph C. (Heliyon, 2022)
    Background: Health care providers (HCPs) have always been a common target of stigmatization during widespread infections and COVID-19 is not an exception. Aim: This study aims to investigate the prevalence of stigmatization ...
  • STIMULI-RESPONSIVE POLYMERS FOR TRANSDERMAL, TRANSMUCOSAL AND OCULAR DRUG DELIVERY 
    Berillo, Dmitriy; Zharkinbekov, Zharylkasyn; Kim, Yevgeniy; Raziyeva, Kamila; Temirkhanova, Kamila; Saparov, Arman (MDPI, 2021-12-01)
    Despite their conventional and widespread use, oral and intravenous routes of drug administration face several limitations. In particular, orally administered drugs undergo enzymatic degradation in the gastrointestinal ...
  • STRESS, ANXIETY AND DEPRESSION IN PARENTS OF CHILDREN WITH AUTISM SPECTRUM DISORDERS IN KAZAKHSTAN: PREVALENCE AND ASSOCIATED FACTORS 
    Alibekova, Raushan; Chan, Chee Kai; Crape, Byron; Kadyrzhanuly, Kainar; Gusmanov, Arnur; An, Sofiya; Bulekbayeva, Sholpan; Akhmetzhanova, Zulfiya; Ainabekova, Assel; Yerubayev, Zhanibek; Yessimkulova, Fariza; Bekisheva, Aislu; Ospanova, Zarina; Rakhimova, Makhabbat (Global Mental Health, 2022-10-11)
    Introduction. Studies worldwide reported increased levels of stress among parents of children with autism due to the unique caregiving challenges. While research has shown that parents’ and autistic child’s demographics ...
  • Stress-Induced Anxiety- and Depressive-Like Phenotype Associated with Transient Reduction in Neurogenesis in Adult Nestin- CreERT2/Diphtheria Toxin Fragment A Transgenic Mice 
    Yun, Sanghee; Donovan, Michael H.; Ross, Michele N.; Richardson, Devon R.; Reister, Robin; Farnbauch, Laure A.; Fischer, Stephanie J.; Riethmacher, Dieter; Gershenfeld, Howard K.; Lagace, Diane C.; Eisch, Amelia J. (PLOS ONE, 2016-01-21)
    Depression and anxiety involve hippocampal dysfunction, but the specific relationship between these mood disorders and adult hippocampal dentate gyrus neurogenesis remains unclear. In both humans with MDD and rodent models ...
  • Stress-Induced Anxiety- and Depressive-Like Phenotype Associated with Transient Reduction in Neurogenesis in Adult Nestin- CreERT2/Diphtheria Toxin Fragment A Transgenic Mice 
    Yun, Sanghee; Donovan, Michael H.; Ross, Michele N.; Richardson, Devon R.; Reister, Robin; Farnbauch, Laure A.; Fischer, Stephanie J.; Riethmacher, Dieter; Gershenfeld, Howard K.; Lagace, Diane C.; Eisch, Amelia J. (Plos One, 2016-01-21)
    Depression and anxiety involve hippocampal dysfunction, but the specific relationship between these mood disorders and adult hippocampal dentate gyrus neurogenesis remains unclear. In both humans with MDD and rodent models ...
  • SURFACE-ENHANCED RAMAN SPECTROSCOPY (SERS) FOR PROTEIN DETERMINATION IN HUMAN URINE 
    Aitekenov, Sultan; Sultangaziyev, Alisher; Ilyas, Aisha; Dyussupova, Aigerim; Boranova, Aigerim; Gaipov, Abduzhappar; Bukasov, Rostislav (Sensing and Bio-Sensing Research, 2022)
    Excessive protein excretion in human urine is an early and sensitive marker of diabetic nephropathy, primary and secondary renal disease. Kidney problems, particularly chronic kidney disease, remain among the few ...
  • SYSTEMATIC REVIEW AND META-ANALYSIS OF INCIDENCE AND PREVALENCE OF ENDOMETRIOSIS 
    Sarria-Santamera, Antonio; Orazumbekova, Binur; Terzic, Milan; Issanov, Alpamys; Chaowen, Chen; Asúnsolo-del-Barco, Angel (MDPI, 2020-12-30)
    There is still much controversy regarding the epidemiology of endometriosis. The objective of this work is to conduct a systematic review, and if possible, proceed with a meta-analysis of studies that have analyzed the ...
  • SYSTEMATIC REVIEW AND META-ANALYSIS OF INCIDENCE AND PREVALENCE OF ENDOMETRIOSIS 
    Sarria-Santamera, Antonio; Orazumbekova, Binur; Terzic, Milan; Issanov, Alpamys; Chaowen, Chen; Asúnsolo-del-Barco, Angel (Healthcare, 2020-12-30)
    There is still much controversy regarding the epidemiology of endometriosis. The objective of this work is to conduct a systematic review, and if possible, proceed with a meta-analysis of studies that have analyzed the ...