A Low-Carbohydrate Diet Improves Glucose Metabolism in Lean Insulinopenic Akita Mice Along With Sodium-Glucose Cotransporter 2 Inhibitor
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Frontiers Media S.A.
Abstract
In lean insulinopenic Akita mice, LC and SGLT2i each reduce hyperglycemia; together they synergistically improve glycemic control and islet morphology without further elevating ketones beyond SGLT2i alone.
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Fujita, Y.; Atageldiyeva, K. K.; Takeda, Y.; Yanagimachi, T.; Makino, Y.; Haneda, M. (2020). Frontiers in Endocrinology, 11:601594. https://doi.org/10.3389/fendo.2020.601594