Our project will test the hypothesis that MTAs will specifically regulate microtubule interactions with EB proteins, thereby regulating MT dynamics. Our strategy is to quantify MTA effects on MT structures, cell spreading ...

The results of our study have indicated that Aβ42 induces expression of P-selectin on the surface of bEnd3 cells and promotes actin polymerization in a time dependent manner, and all these events correlate with ROS generation. ...

The ultimate goal of fundamental biomedical research is to decipher mechanisms underlying the impairment of molecules, cells, tissues, and organs and subsequent dysfunction of the whole human body. Knowledge of these ...