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Browsing by Author "Riethmacher, Dieter"

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Peripheral nervous system defects in erbB2 mutants following genetic rescue of heart development

Woldeyesus, Masresha T.; Britsch, Stefan; Riethmacher, Dieter; Xu, Lan; Sonnenberg-Riethmacher, Eva; Abou-Rebyeh, Faikah; Harvey, Richard; Caroni, Pico; Birchmeier, Carmen (Cold Spring Harbor Laboratory Press, 1999)

The ErbB2 tyrosine kinase functions as coreceptor for the neuregulin receptors ErbB3 and ErbB4 and can participate in signaling of EGF receptor (ErbB1), interleukin receptor gp130, and G-protein coupled receptors. ErbB2−/− ...
Promotion of periostin expression contributes to the migration of Schwann cells

Sonnenberg-Riethmacher, Eva; Miehe, Michaela; Riethmacher, Dieter (The Company of Biologists Ltd, 2015)

Neuregulin ligands and their ErbB receptors are important for the development of Schwann cells, the glial cells of the peripheral nervous system (PNS). ErbB3 deficiency is characterized by a complete loss of Schwann ...
Reallocation of Olfactory Cajal-Retzius Cells Shapes Neocortex Architecture

de Frutos, Cristina A.; Bouvier, Guy; Arai, Yoko; Thion, Morgane S.; Lokmane, Ludmilla; Keita, Maryama; Garcia-Dominguez, Mario; Charnay, Patrick; Hirata, Tatsumi; Riethmacher, Dieter; Grove, Elizabeth A.; Tissir, Fadel; Casado, Mariano; Pierani, Alessandra; Garel, Sonia (Neuron, 2016-10-19)

Summary The neocortex undergoes extensive developmental growth, but how its architecture adapts to expansion remains largely unknown. Here, we investigated how early born Cajal-Retzius (CR) neurons, which regulate the ...
Sebaceous lipids are essential for water repulsion, protection against UVB-induced apoptosis and ocular integrity in mice

Dahlhoff, Maik; Camera, Emanuela; Schäfer, Matthias; Emrich, Daniela; Riethmacher, Dieter; Foster, April; Paus, Ralf; Schneider, Marlon R. (Development (Cambridge), 2016-05-15)

Sebocytes, which are characterized by lipid accumulation that leads to cell disruption, can be found in hair follicle-associated sebaceous glands (SGs) or in free SGs such as the Meibomian glands in the eyelids. Because ...
Stress-Induced Anxiety- and Depressive-Like Phenotype Associated with Transient Reduction in Neurogenesis in Adult Nestin- CreERT2/Diphtheria Toxin Fragment A Transgenic Mice

Yun, Sanghee; Donovan, Michael H.; Ross, Michele N.; Richardson, Devon R.; Reister, Robin; Farnbauch, Laure A.; Fischer, Stephanie J.; Riethmacher, Dieter; Gershenfeld, Howard K.; Lagace, Diane C.; Eisch, Amelia J. (PLOS ONE, 2016-01-21)

Depression and anxiety involve hippocampal dysfunction, but the specific relationship between these mood disorders and adult hippocampal dentate gyrus neurogenesis remains unclear. In both humans with MDD and rodent models ...
Stress-Induced Anxiety- and Depressive-Like Phenotype Associated with Transient Reduction in Neurogenesis in Adult Nestin- CreERT2/Diphtheria Toxin Fragment A Transgenic Mice

Yun, Sanghee; Donovan, Michael H.; Ross, Michele N.; Richardson, Devon R.; Reister, Robin; Farnbauch, Laure A.; Fischer, Stephanie J.; Riethmacher, Dieter; Gershenfeld, Howard K.; Lagace, Diane C.; Eisch, Amelia J. (Plos One, 2016-01-21)

Depression and anxiety involve hippocampal dysfunction, but the specific relationship between these mood disorders and adult hippocampal dentate gyrus neurogenesis remains unclear. In both humans with MDD and rodent models ...
The c-ros tvrosine kinase receptor I controls regionalization and differehiation of epithelial cells in the epididymis

Sonnenberg-Riethmacher, Eva; Walter, Barbara; Riethmacher, Dieter; Godecke, Stephanie; Birchmeie, Carmen (Cold Spring Harbor Laboratory Press, 1996)

The c-ros gene was originally identified in mutant form as an oncogene. The proto-oncogene encodes a tyrosine kinase receptor that is expressed in a small number of epithelial cell types, including those of the epididymis. ...
The extracellular-matrix protein matrilin 2 participates in peripheral nerve regeneration

Malin, Dmitry; Sonnenberg-Riethmacher, Eva; Guseva, Daria; Wagener, Raimund; Aszódi, Attila; Irintchev, Audrey; Riethmacher, Dieter (The Company of Biologists, 2009)

Matrilins are adaptor proteins of the extracellular matrix involved in the formation of both collagen-dependent and collagen-independent filamentous networks. Although their molecular structure and binding partners have ...