Almost one third of the world's population is infected with Mycobacterium tuberculosis
(MTB) and only 10% of them will develop any active form of the disease. TB is second (1s t is HIV/AIDS)
greatest killer worldwide due ...
Ventricular tachycardia (VT) is a common symptom in cardiac disorders of
different etiology. Abnormalities of ion channels are attributed to mutations in the genes
encoding the channel protein and cause altered function ...
The next generation sequencing technology provides a tool to obtain genetic data from clinically isolates M.tuberculosis. Using it we can clarify the factors cause of the formation of highly virulent strains of M.tuberculosis, ...
Correction of phenotypic plasticity of macrophages for reprogramming inflammatory
response is of great interest to modern medicine. To date, there are lots of factors, which can
alter macrophages' phenotype to M1 or M2. ...
The aim of the project is to define genetic architecture of Kazakh population by sequencing and analyzing whole exomes and whole genomes of Kazakhs living in different regions of Kazakhstan
In this study combined design was used, which included: 1) Case-control study; 2) Molecular epidemiological study; and 3) Study of human genetic susceptibility to tuberculosis.This work is the first case-control study in ...
The purpose of this project is to develop a system capable of eliminating the bacterial infection in clinical environment, by means of new type of wound dressing based on macroporous polymer hydrogel matrix. The matrix has ...
Haemoperfusion (HP), or blood purification via adsorption, has been introduced
almost at the same time as haemodialysis in 1960s. HP compared to dialysis does not introduce
any substances into the body and only removes ...
Saliev, T.; Illsley, M.; Akhmetova, A.; Nurgozhin, T.; Mikhalovsky, S. V.(Nazarbayev University, 2014)
The combination "cryogel + nanoparticles" allows developing a new type of wound
dressing, where antimicrobial properties of silver nanoparticles made have been utilized. Previous reports
have shown that the production ...
Students face challenges during the first year at university. Some students find it
difficult to adapt to the new environment, while others have a smoother transition to university life.
Master program students at Graduate ...
The project is aimed to create the prerequisites for a personalized approach to the diagnosis
and treatment of tuberculosis (TB) by identifying and comparing the whole genome sequences of
M.tuberculosis strains isolated ...