Browsing by Subject "nucleotide excision repair"

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ROLE OF BASE EXCISION REPAIR PATHWAY IN THE PROCESSING OF COMPLEX DNA DAMAGE GENERATED BY OXIDATIVE STRESS AND ANTICANCER DRUGS

Baiken, Yeldar; Kanayeva, Damira; Taipakova, Sabira; Groisman, Regina; Ishchenko, Alexander A.; Begimbetova, Dinara; Matkarimov, Bakhyt; Saparbaev, Murat (Frontiers in Cell and Developmental Biology, 2021-01-22)

Chemical alterations in DNA induced by genotoxic factors can have a complex nature such as bulky DNA adducts, interstrand DNA cross-links (ICLs), and clustered DNA lesions (including double-strand breaks, DSB). Complex ...