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Browsing by Subject "IL-6/11-STAT3"

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ZEB1 and IL-6/11-STAT3 signalling cooperate to define invasive potential of pancreatic cancer cells via differential regulation of the expression of S100 proteins

Al-Ismaeel, Qais; Neal, Christopher P.; Al-Mahmoodi, Hanaa; Almutairi, Zamzam; Al-Shamarti, Ibtihal; Straatman, Kees; Jaunbocus, Nabil; Irvine, Andrew; Issa, Eyad; Moreman, Catherine; Dennison, Ashley R.; Sayan, A. Emre; McDearmid, Jonathan; Greaves, Peter; Tulchinsky, Eugene; Kriajevska, Marina (NATURE PUBLISHING GROUP, 2019-07-02)

Background S100 proteins have been implicated in various aspects of cancer, including epithelial-mesenchymal transitions (EMT), invasion and metastasis, and also in inflammatory disorders. Here we examined the impact of ...