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Browsing by Author "ab017814-8d72-49d5-aa17-85126128e179"

Browsing by Author "ab017814-8d72-49d5-aa17-85126128e179"

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  • Anticancer Effects and uses of Melatonin A Review 
    Mektepbayeva, Damel; Alibek, Kenneth; Atinbayeva, N.; Irving, S; Zhaisanbayeva, B; Mussurova, S; Mussakhan, S (Austin Journal of Cancer and Clinical Research, 2015-08)
    Melatonin (N-acetyl-5-methoxytryptamine, MLT) is a naturally occurring hormone secreted by the pineal gland. Clinical evidence suggests that MLT may have a possible role in the treatment of cancer, where MLT presents many ...
  • Disruption of Bcl-2 and Bcl-xL by viral proteins as a possible cause of cancer 
    Alibek, Kenneth; Irving, Stephanie; Sautbayeva, Zarina; Kakpenova, Ainur; Bekmurzayeva, Aliya; Baiken, Yeldar; Imangali, Nurgul; Shaimerdenova, Madina; Mektepbayeva, Damel; Balabiyev, Arnat; Chinybayeva, Aizada (Infectious Agents and Cancer, 2014)
    The Bcl proteins play a critical role in apoptosis, as mutations in family members interfere with normal programmed cell death. Such events can cause cell transformation, potentially leading to cancer. Recent discoveries ...
  • The effects of antiviral treatment on breast cancer cell line 
    Mektepbayeva, Damel; Shaimerdenova, Madina; Karapina, Orynbassar; Alibek, Kenneth; Akilbekova, Dana (Infectious Agents and Cancer, 2017)
    Background: Recent studies have revealed the positive antiproliferative and cytotoxic effects of antiviral agents in cancer treatment. The real effect of adjuvant antiviral therapy is still controversial due to the lack ...
  • Open Access Week 
    Mektepbayeva, Damel (Nazarbayev University Library and It Services, 2018-10-15)
  • Retinal Targets ALDH Positive Cancer Stem Cell and Alters the Phenotype of Highly Metastatic Osteosarcoma Cells 
    Mu, Xiaodong; Mektepbayeva, Damel; Patel, Stuti; Mahjoub, Adel; Huard, Johnny; Weiss, Kurt (Sarcoma, 2015)
    Aldehyde dehydrogenase (ALDH) is a cancer stem cell marker. Retinoic acid has antitumor properties, including the induction of apoptosis and inhibition of proliferation. Retinal, the precursor of retinoic acid, can be ...