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EARLY VERSUS LATE TIME-RESTRICTED EATING AS A NEW APPROACH FOR PREVENTION OF CARDIOVASCULAR DISEASES.
(Nazarbayev University School of Medicine, 2024) Ibraimova, Ilvira
Worldwide, cardiovascular diseases (CVD) are a common problem, which can be avoided by changing eating habits. Time restricting eating (TRE), which is the subtype of intermittent fasting (IF), is based on the idea of eating within defined time intervals daily. Evidence shows that TRE results in CVDs risk reduction by improving lipid composition, decreasing inflammation, and reducing blood pressure levels. Also, the combination of TRE diet with our bodies’ inner biological clock, meaning circadian rhythm increases the success of reduction of weight and CVD risk factors. The main goal of this pilot study is to compare the effectiveness of early TRE with late TRE in weight reduction and improving CVDs risk factors. This study was conducted among general population of Astana and included 34 healthy participants. This is a randomized cross-over study and participants were randomly divided into the early TRE group (eating window by 5 pm) and late TRE group (eating window from 12 pm) with an eating window of 6-8 hours. The participants went through 2 weeks preparation phase, 4 weeks of the TRE phase, 2 weeks of the washout period, and 4 weeks of switched TRE phase. The results showed that early TRE resulted in greater decrese in BMI and LDL levels in comparison with the late TRE