Rational design of new chemical drugs based on compounds that block the pores in cell membranes
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Date
2013
Authors
Kakpenova, A.
Zhanbossinova, A.
Negmetzhanov, B.
Tauanov, Z.
Karginov, V.
Adilov, S.
Alibek, K.
Journal Title
Journal ISSN
Volume Title
Publisher
Nazarbayev University
Abstract
“Rational Drug Design” method is a new principle and methodology in producing pharmaceuticals based on precise and structure-oriented approach. The proposed method is based on principle of blocking the pores caused by Staphylococccus aureus (S. aureus) toxins in the membranes of host cells [1]. Design of β-cyclodextrin derivatives with precise geometry might be used for production of antibacterial and prophylactic pharmaceuticals against S. aureus infection.
Description
Keywords
first research week, chemical drugs, pharmaceuticals, Staphylococccus aureus infection