ORIGINAL METHODOLOGY OF ANNULOPLASTY OF THE MITRAL VALVE WITH A STABILIZED AUTOPERICARDIUM IN DEGENERATIVE HEART DISEASES
Loading...
Date
2020
Authors
Zhurko, S.
Olzhayev, F.
Gamzaev, A.
Fedorov, S.
Pimenova, P.
Journal Title
Journal ISSN
Volume Title
Publisher
International conference "MODERN PERSPECTIVES FOR BIOMEDICAL SCIENCES: FROM BENCH TO BEDSIDE”; National Laboratory Astana
Abstract
Introduction: We have evaluated the results of using stabilized autopericardium for the correction of
the mitral valve (MV) defects in patients with degenerative heart diseases.
Methods: For the period from 2017-2019, MV plasty was performed in 51patients with a strip of autopericardium
according to the original method. Among the patients who underwent surgery, men prevailed
64.7% (33). The average age is 55.6 (36 to 78) years. A strip 12x0.5mm in size was cut from the
patient’s pericardium. Autopericardium stabilization was carried out by treatment with a 0.6% glutaraldehyde
solution for 10 minutes. Processing of the autopericardium with glutaraldehyde allows preserving
the positive properties of the autopericardium to eliminate the inconvenience of manipulating the autopericardial
strip, increase its strength, reduce the cellular response from the body and prevent denaturation
of the collagen fibers. Our proposed technique allows us to determine the optimal length of the
strip, individually for each patient. Correction was considered adequate if, after surgery, regurgitation on
MV did not exceed I degree.
Results: No mortality was observed at the hospital stage. In one case, an early relapse of MV failure
occurred, but the degree of mitral regurgitation did not exceed II degree and the patient was under observation.
Conclusions: The use of a stabilized autopericardium as a material for the reconstruction of MV with
an individual selection of the strip length allows increasing the strength of the fibrous ring and achieving
optimal MV functioning and significantly improving tissue-specific biocompatibility of the autoimplant.
The clinical results obtained using the original MV annuloplasty technique demonstrated high efficiency,
low mortality and improved results of the correction of degenerative heart diseases and could be recommended
for extensive clinical use in cardiac surgery.
Description
Keywords
mitral valve, stabilized autopericardium, Research Subject Categories::MEDICINE