Specific and reliable detection of Myosin 1C isoform A by RTqPCR in prostate cancer cells
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Date
2018-11-20
Authors
Saidova, Aleena A.
Potashnikova, Daria M.
Tvorogova, Anna V.
Maly, Ivan V.
Hofmann, Wilma A.
Vorobjev, Ivan A.
Journal Title
Journal ISSN
Volume Title
Publisher
PeerJ Chemistry Journals
Abstract
Prostate cancer (PC) diagnostics and treatment often present a challenging task due to cancer subtype heterogeneity and differential disease progression in patient subgroups. Hence, the critical issue is finding a reliable and sensitive diagnostic and prognostic PC marker, especially for cases of biopsies with low percentages of cancer cells. Isoform A of myosin 1C was shown to be expressed in PC cells and responsible for their invasive properties, however, its feasibility for diagnostic purposes remains to be elucidated.....
Description
Keywords
Prostate cancer, myosin 1C A isoform
Citation
Saidova AA, Potashnikova DM, Tvorogova AV, Maly IV, Hofmann WA, Vorobjev IA. 2018. Specific and reliable detection of Myosin 1C isoform A by RTqPCR in prostate cancer cells. PeerJ 6:e5970 https://doi.org/10.7717/peerj.5970