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Шығу күні бойынша Articles көру
Көрінетін элементтер 1-20 из 88
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(Nazarbayev University School of Sciences and Humanities, 2013-05-23)Nicotinic acetylcholine receptors (nAChRs) containing the α9 subunit are expressed in a wide variety of non-neuronal tissues ranging from immune cells to breast carcinomas. The α9 subunit is able to assemble into a functional ...
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(Nazarbayev University School of Sciences and Humanities, 2017-03-30)We compared the susceptibility to viral infection of splenocytes, isolated from young versus old CBA mice, and evaluated the antiviral actions of lactoferrin in splenocytes infected with Encephalomyocarditis virus (EMCV). ...
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(Nazarbayev University School of Sciences and Humanities, 2017-12-01)Extracellular vesicle (EV) production is a universal feature of metazoan cells as well as prokaryotes (bMVs - bacterial microvesicles). They are small vesicles with phospholipid membrane carrying proteins, DNA and different ...
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(Nazarbayev University School of Sciences and Humanities, 2017-12-28)Background: Kazakhstan belongs to countries with a high level of brucellosis among humans and farm animals. Although antibiotic therapy is the main way to treat acute brucellosis in humans there is still little information ...
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(AIMS Press, 2018)Microtubules in interphase fibroblast-like cells are thought to be organized in a radial array growing from a centrosome-based microtubule-organizing center (MTOC) to the cell edges. However, many morphogenetic processes ...
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(Nazarbayev University School of Sciences and Humanities, 2018-01-19)The 16th International Conference on Bioinformatics (InCoB) was held at Tsinghua University, Shenzhen from September 20 to 22, 2017. The annual conference of the Asia-Pacific Bioinformatics Network featured six keynotes, ...
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(Nazarbayev University School of Sciences and Humanities, 2018-01-28)Although it has been demonstrated that cAMP pathway affect both adaptive and innate cell functions, the role of this pathway in the regulation of T-cell-mediated central nervous system (CNS) autoimmune inflammation, such ...
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(Nazarbayev University School of Sciences and Humanities, 2018-05-28)The alarming rise in the prevalence of antibiotic resistance among pathogenic bacteria poses a unique challenge for the development of effective therapeutic agents. Antimicrobial peptides (AMPs) have attracted a great deal ...
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(Nazarbayev University School of Sciences and Humanities, 2018-07-01)Imaging flow cytometry (IFC) captures multichannel images of hundreds of thousands of single cells within minutes. IFC is seeing a paradigm shift from low- to high-information-content analysis, driven partly by deep learning ...
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(ELSEVIER, 2018-08-24)Stainless steel (SS) is widely used in many biomedical applications including bone implants and cardiovascular stents due to its good mechanical properties, biocompatibility and low price. Surface modification allows ...
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(PeerJ Chemistry Journals, 2018-11-20)Prostate cancer (PC) diagnostics and treatment often present a challenging task due to cancer subtype heterogeneity and differential disease progression in patient subgroups. Hence, the critical issue is finding a reliable ...
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(Nazarbayev University School of Sciences and Humanities, 2018-11-28)The importance of myeloid cells in HIV transmission in the female genital tract is uncertain. Because it is difficult to study the early events in HIV transmission in humans, most of our knowledge is based on animal models ...
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(Biology Open, 2018-12-13)When cells with a mesenchymal type of motility come into contact with an adhesive substrate they adhere and start spreading by the formation of lamellipodia. Using a label-free approach and virtual synchronization approach ...
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(Nazarbayev University School of Sciences and Humanities, 2019-01-30)BackgroundSome membrane proteins can translocate into the nucleus, defined as nuclear localized membrane proteins (NLMPs), including receptor tyrosine kinases (RTKs). We previously showed that nuclear MET (nMET), a member ...
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(Nazarbayev University School of Sciences and Humanities, 2019-02-20)Thirty-five years ago, we described fragmentation of the mitochondrial population in a living cell into small vesicles (mitochondrial fission). Subsequently, this phenomenon has become an object of general interest due to ...
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(Journal of Medicinal Chemistry, 2019-03-27)For many individuals, in particular during winter, supplementation with the secosteroid vitamin D3 is essential for the prevention of bone disorders, muscle weakness, autoimmune diseases, and possibly also different types ...
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(SPANDIDOS, 2019-04)The serine protease cathepsin G (CatG) is involved in numerous processes associated with the innate and adaptive immune system. During an immune response, neutrophils secrete CatG, which can bind to the cell surface of ...
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(Nazarbayev University School of Sciences and Humanities, 2019-04-18)Nuclear receptor tyrosine kinases (nRTKs) are aberrantly upregulated in many types of cancers, but the regulation of nRTK remains unclear. We previously showed androgen deprivation therapy (ADT) induces nMET in ...
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(Nazarbayev University School of Sciences and Humanities, 2019-04-18)InCoB, one of the largest annual bioinformatics conferences in the Asia-Pacific region since its launch in 2002, returned to New Delhi, India after 12 years, with a conference attendance of 314 delegates. The 2018 conference ...
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(FRONTIERS MEDIA, 2019-04-24)Microtubule (MT) inhibitors show anti-cancer activity in a wide range of tumors in vitro and demonstrate high clinical efficacy. To date they are routinely included into many chemotherapeutic regimens. While the mechanisms ...
Көрінетін элементтер 1-20 из 88
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