Browsing by Author "b586f6bb-405c-401b-a0df-be5043eeb99c"

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AN IN SILICO APPROACH TO ANALYZE HCV GENOTYPE‑SPECIFC BINDING‑SITE VARIATION AND ITS EFECT ON DRUG–PROTEIN INTERACTION

Khalid, Ramsha; Anwar, Muhammad Faraz; Raees, Muhammad Aanish; Naeem, Sadaf; Abidi, Syed Hani; Ali, Syed (Nature Research, 2020-11-30)

Genotype variation in viruses can afect the response of antiviral treatment. Several studies have established approaches to determine genotype-specifc variations; however, analyses to determine the efect of these variations ...
Simian Virus 40 Large T Antigen as a Model to Test the Efficacy of Flouroquinolones against Viral Helicases

Siddiqui, Sammer; Anwar, Muhammad F.; Naeem, Sadaf; Abidi, Syed Hani; Zarina, Shamshad; Ali, Syed (Biomedical Informatics, 2018-02-28)

Simian virus 40 large T-antigen (SV40 LT-Ag) is a 708 amino acid nuclear phosphoprotein. Among many functions of LT-Ag is its ability to perform as an ATPase-helicase, catalyzing the unwinding of viral genome during ...