Aljofan M.Issayev A.Sergazy S.Zhetkenev S.2024-10-312024-10-312022Aljofan M., Issayev A., Sergazy S., Zhetkenev S. (2022). Establishment and validation of mare’s milkderived exosomes extraction method. (pp. S111-S112). In 15th Congress of the European Association for Clinical Pharmacology and Therapeutics (EACPT). European Journal of Clinical Pharmacology, 78(S1), 1–163, Springer. https://doi.org/10.1007/s00228-022-03333-yhttps://link.springer.com/article/10.1007/s00228-022-03333-yhttps://nur.nu.edu.kz/handle/123456789/8285Exosomes are nanosized (30-150nm) extracellular vesicles with double layer lipid membrane, that present in milk of farm animals. These vesicles maintain endocrine, paracrine and autocrine signaling. They produced by parental cell as major substance of cell-cell communications. Their main physiological function is to transmit cellular signals and are capable of carrying big and charged molecules, which otherwise would not be able to penetrate the plasma membraneenCC0 1.0 UniversalExtracellular vesiclesdrug deliverydrug discoveryArticle