2015-10-292015-10-292013http://nur.nu.edu.kz/handle/123456789/578Our project will test the hypothesis that MTAs will specifically regulate microtubule interactions with EB proteins, thereby regulating MT dynamics. Our strategy is to quantify MTA effects on MT structures, cell spreading and cell motility while controlling EB1 and EB3 expression during high-resolution time lapsed imaging.enfirst research weekcellshealthcare problemsinnovative scientific researchmicrotubule-targeting agentsChemotherapeutic`s effects on cell speading and motility via regulation of microtubule binding proteinsAbstract