Myngbay, A.Bexeitov, Y.Adilbayeva, A.Yevstratenko, B. P.Aitzhanova, R. M.Otarbayev, N. K.Adarichev, V.A.2016-05-302016-05-302016-05A. Myngbay, Y. Bexeitov, A. Adilbayeva, B. P. Yevstratenko, R. M. Aitzhanova, N. K. Otarbayev, and V.A. Adarichev. 2016. Elevated levels of plasma collagen priple helix repeat-containing (CTHRC1) protein correlates with increased granul ocytopoiesis and higher rheumatoid arthritis disease severity score. Abstract book. 4 th International Scientific Conference “Regenerative medicine & healthy aging”. National Laboratory Astana, Nazarbayev University. http://nur.nu.edu.kz/handle/123456789/1521http://nur.nu.edu.kz/handle/123456789/1521Monitoring and suppressing activity of the pathological granulating pannus tissue is essential for Rheumatoid Arthritis (RA) management. Synovial joints pain and tissue destruction is a derivative of the pannus activity. In a mouse model for RAwe found CTHRC1, a secreted and circulating protein, to be inducible in arthritis and correlated with the disease severity. We performed a clinical investigation to ascertain the role of CTHRC1 in the progression of the disease.enAttribution-NonCommercial-ShareAlike 3.0 United StatesRheumatoid ArthritisAbstract