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CURRENT ROLE OF PIPELLE ENDOMETRIAL SAMPLING IN EARLY DIAGNOSIS OF ENDOMETRIAL CANCER

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dc.contributor.author Terzic, Milan Milosav
dc.contributor.author Aimagambetova, Gulzhanat
dc.contributor.author Terzic, Sanja
dc.contributor.author Norton, Melanie
dc.contributor.author Bapayeva, Gauri
dc.contributor.author Garzon, Simone
dc.date.accessioned 2021-01-27T05:10:49Z
dc.date.available 2021-01-27T05:10:49Z
dc.date.issued 2020-12
dc.identifier.citation Terzic, M. M., Aimagambetova, G., Terzic, S., Norton, M., Bapayeva, G., & Garzon, S. (2020). Current role of Pipelle endometrial sampling in early diagnosis of endometrial cancer. Translational Cancer Research, 9(12), 7716–7724. https://doi.org/10.21037/tcr.2020.04.20 en_US
dc.identifier.issn 2219-6803
dc.identifier.uri https://doi.org/10.21037/tcr.2020.04.20
dc.identifier.uri https://tcr.amegroups.com/article/view/38458/html
dc.identifier.uri http://nur.nu.edu.kz/handle/123456789/5246
dc.description.abstract Endometrial cancer is the most common gynecologic cancer in developed countries. The most prevalent, however not pathognomonic symptom of the disease is abnormal uterine bleeding. The diagnosis of endometrial cancer is based on the histologic results of endometrial sampling. Endometrial biopsy could be obtained using different modalities: hysteroscopy-directed endometrial biopsy, uterine curettage or office endometrial biopsy. Outpatient endometrial biopsy using different devices for the evaluation of abnormal uterine bleeding is gaining popularity. The most popular office-based device for endometrial sampling procedure is the Pipelle device. Currently, Pipelle endometrial sampling is widely used to diagnose endometrial cancer in women with abnormal uterine bleeding and/or postmenopausal bleeding. The method became very useful due to easiness and simplicity of the procedure, availability of a device, as well as high sensitivity in detecting endometrial cancer. Many studies compared the validity and accuracy of Pipelle biopsy with dilation and curettage in the detection of various endometrial pathologies. Published results state that Pipelle biopsy and uterine curettage are almost equally reliable in the evaluation of endometrial pathologies. Moreover, Pipelle biopsy appears more beneficial as it does not require hospital admission and anaesthesia. However, it is proven the Pipelle technique has a limited capacity to identify endometrial polyps, and some authors, based on their study, claim that dilation and curettage is a more reliable method in terms of correlation with the final histological results. In addition, there are many factors affecting the efficiency of the endometrial biopsy. Failure to get samples that are adequate for histological examination is one of the problems associated with Pipelle sampling. The above mentioned contradictory conclusions by different researchers and lack of guidance to avoid inadequate sampling present the demand for further studies on the comparison of Pipelle biopsy and uterine curettage efficiency and accuracy. en_US
dc.language.iso en en_US
dc.publisher AME Publishing en_US
dc.relation.ispartofseries Translational Cancer Research;Vol 9, No 12 (December 2020)
dc.rights Attribution-NonCommercial-ShareAlike 3.0 United States *
dc.rights.uri http://creativecommons.org/licenses/by-nc-sa/3.0/us/ *
dc.subject Dilation and curettage en_US
dc.subject early diagnosis en_US
dc.subject endometrial cancer en_US
dc.subject endometrial sampling en_US
dc.subject Pipelle biopsy en_US
dc.subject Research Subject Categories::MEDICINE en_US
dc.title CURRENT ROLE OF PIPELLE ENDOMETRIAL SAMPLING IN EARLY DIAGNOSIS OF ENDOMETRIAL CANCER en_US
dc.type Article en_US
workflow.import.source science


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