Browsing Abstracts by Subject "targeted NGS"

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POTASSIUM CHANNEL GENES KCNQ1, KCNE1/2, KCNH2 (HERG) MUTATIONS IN PATIENTS WITH ATRIAL FIBRILLATION IN KAZAKHSTAN

Abilova, Zhannur; Rakhimova, Saule; Akhmetova, Ainur; Zhalbinova, Madina; Nuralinov, Omirbek; Rashbayeva, Gulzhaina; Akilzhanova, Gulbanu; Abdrakhmanov, Ayan; Bekbosynova, Mahabbat; Akilzhanova, Ainur (International conference "MODERN PERSPECTIVES FOR BIOMEDICAL SCIENCES: FROM BENCH TO BEDSIDE”; National Laboratory Astana, 2020)

Background: Atrial fibrillation (AF) is a common arrhythmia of substantial public health importance, a major risk factor for stroke, heart failure, and other cardiovascular morbidities. Recent evidence demonstrates a ...
TARGETED NEXT GENERATION SEQUENCING REVEALS NEW INSIGHTS INTO THE GENETIC BASIS OF INHERITED ARRHYTHMIA IN KAZAKHSTANI PATIENTS

Akilzhanova, A.; Guelly, C.; Abilova, Zh.; Rakhimova, S.; Akhmetova, A.; Kairov, U.; Trajanoski, S.; Akilzhanova, G.; Kozhamkulov, U.; Abdrakhmanov, A.; Bekbosynova, M. (International conference "MODERN PERSPECTIVES FOR BIOMEDICAL SCIENCES: FROM BENCH TO BEDSIDE”; National Laboratory Astana, 2020)

Introduction:Ventricular arrhythmias are caused by mutations of ion channels and their interacting proteins. Most arrhythmia syndromes are inherited in an autosomal dominant manner, such that first-degree family members ...