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Browsing Abstracts by Issue Date

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  • УЛЬТРАСТРУКТУРА МОНОНУКЛЕАРНОЙ ФРАКЦИИ КЛЕТОК КОСТНОГО МОЗГА У БОЛЬНЫХ С ХРОНИЧЕСКОЙ АУТОИММУННОЙ ПАТОЛОГИЕЙ ДО И ПОСЛЕ КУЛЬТИВИРОВАНИЯ 
    Федотовских, Г.В.; Шаймарданова, Г.М.; Аскаров, М.Б.; Ежеленко, Т.Г.; Марат, С. (International conference "MODERN PERSPECTIVES FOR BIOMEDICAL SCIENCES: FROM BENCH TO BEDSIDE”; National Laboratory Astana, 2020)
    Введение: Аутологичные клетки костного мозга больных с хронической аутоиммунной патологией характеризуются снижением биорегуляторной активности и мало пригодны для клеточной терапии. Важным способом повышения функциональной ...
  • МЕСТНОЕ ПРИМЕНЕНИЕ ПОЛИНУКЛЕОТИДА СТАБИЛИЗИРОВАННОГО В ГИДРОГЕЛЕ ДЛЯ ЛЕЧЕНИЯ РАН В УСЛОВИЯХ ЭКСПЕРИМЕНТАЛЬНОГО САХАРНОГО ДИАБЕТА 
    Дмитриева, М.В.; Толеубаев, М.Т.; Кожахметов, С.К.; Игисинов, Н.С.; Николаева, О.Г. (2020)
    Введение: Известно, что полинуклеотиды повышают пролиферацию клеток, стимулируя восстановление тканей. Гидрогель на основе карбоксиметилцеллюлозы выступает как носитель лекарственного вещества, обеспечивая контролируемое ...
  • CRYOGELS CONTAINING POLYELECTROLYTE COMPLEX FOR TISSUE ENGINEERING 
    Berillo, D.; Zheng, Y. (International conference "MODERN PERSPECTIVES FOR BIOMEDICAL SCIENCES: FROM BENCH TO BEDSIDE”; National Laboratory Astana, 2020)
    The design of scaffolds for tissue engineering is an important task. The focus of our research is the design of various biocompatible scaffolds based on natural polymers such as gelatin, chitosan and casein using ...
  • DELIVERY OF MONOCLONAL ANTIBODIES FROM MICROENCAPSULATED CELLS 
    Ashimova, A.; Hortelano, G. (International conference "MODERN PERSPECTIVES FOR BIOMEDICAL SCIENCES: FROM BENCH TO BEDSIDE”; National Laboratory Astana, 2020)
    Monospecific immunoglobulins (monoclonal antibodies, MAb) of therapeutic interest have received significant attention since their development by Milstein and Kohler in 1975. The exquisite specificity of MAb, or the ability ...
  • ANAEROBIC FAT FILTERS IN REGENERATIVE MEDICINE 
    Храмцова, Н.И.; Плаксин, С.А.; Храмцов, А.А.; Соцков, А.Ю.; Пономарев, Д.Н. (International conference "MODERN PERSPECTIVES FOR BIOMEDICAL SCIENCES: FROM BENCH TO BEDSIDE”; National Laboratory Astana, 2020)
    Introduction: Adipose tissue is widely used in plastic, aesthetic and regenerative surgery. Autologous fat grafting is one of the most populat procedures in modern surgery. Adipose tissue is usually harvested by lipectomy ...
  • WHOLE TRANSCRIPTOME SEQUENCING ANALYSIS OF PATIENTS WITH ESOPHAGEAL SQUAMOUS CELL CARCINOMA FROM KAZAKHSTAN 
    Sharip, A.; Rakhimova, S.; Molkenov, A.; Kozhamkulov, U.; Zhukov, Y.; Omarov, M.; Akilzhanova, A.; Kairov, U. (International conference "MODERN PERSPECTIVES FOR BIOMEDICAL SCIENCES: FROM BENCH TO BEDSIDE”; National Laboratory Astana, 2020)
    Introduction: Esophageal cancer is the sixth most common cancer in Kazakhstan, and usually not detected until it has progressed to an advanced incurable stage. The predominant histological subtype of esophageal cancer ...
  • LAUNCH OF Q-SYMPHONY BIOINFORMATICS COMPUTING SYSTEM: A HIGH-PERFORMANCE CLUSTER FOR ANALYSIS OF LARGE-SCALE GENOMIC DATASETS 
    Molkenov, A.; Daniyarov, A.; Sharip, A.; Seisenova, A.; Karabayev, D.; Kairov, U. (International conference "MODERN PERSPECTIVES FOR BIOMEDICAL SCIENCES: FROM BENCH TO BEDSIDE”; National Laboratory Astana, 2020)
    Introduction: One whole human genome, provided by next generation sequencing platforms, in raw format takes 20 to 50 GB. In the course of bioinformatics analysis and data analysis, the data volume increases to 300-500 ...
  • IDENTIFICATION OF KAZAKH SPECIFIC GENOMIC VARIANTS USING COMPARATIVE GENOMICS ANALYSIS 
    Molkenov, A.; Daniyarov, A.; Sharip, A.; Seisenova, A.; Karabayev, D.; Kairov, U. (International conference "MODERN PERSPECTIVES FOR BIOMEDICAL SCIENCES: FROM BENCH TO BEDSIDE”; National Laboratory Astana, 2020)
    Introduction: The modern development of high-performance genomic technologies opens up new possibilities for studying the human genome. Large-scale genomic research generates huge amounts of data, the active development ...
  • META-ANALYSIS OF CANCER TRANSCRIPTOMES USING INDEPENDENT COMPONENT ANALYSIS 
    Seisenova, A.; Sharip, A.; Molkenov, A.; Daniyarov, A.; Karabayev, D.; Kairov, U. (International conference "MODERN PERSPECTIVES FOR BIOMEDICAL SCIENCES: FROM BENCH TO BEDSIDE”; National Laboratory Astana, 2020)
    Introduction: Independent Component Analysis (ICA) is a matrix factorization method for data dimension reduction. ICA has been widely applied for the analysis of transcriptomic data for blind separation of biological, ...
  • MULTIDRUG-RESISTANT TUBERCULOSIS: WHOLE-GENOME SEQUENCING AND BIOINFORMATICS ANALYSIS 
    Kairov, U.; Kozhamkulov, U.; Daniyarov, A.; Molkenov, A.; Akhmetova, A.; Rakhimova, S.; Akilzhanova, A. (International conference "MODERN PERSPECTIVES FOR BIOMEDICAL SCIENCES: FROM BENCH TO BEDSIDE”; National Laboratory Astana, 2020)
    Introduction:Tuberculosis (TB) remains a serious public health threat worldwide. It is estimated that approximately one-third of the world’s population has been infected with multidrug-resistant tuberculosis (MDR-TB), ...
  • ИСПОЛЬЗОВАНИЕ НЕЙРОСЕТЕВОГО МОДЕЛИРОВАНИЯ ДЛЯ РАННЕГО ПРОГНОЗИРОВАНИЯ ПАРКИНСОНИЧЕКОГО СИНДРОМА ПРИ ХРОНИЧЕСКОЙ ИШЕМИИ МОЗГА 
    Андронова, М.А.; Статинова, Е.А.; Сайко, Д.Ю.; Андронова, И.А.; Черний, Т.В. (International conference "MODERN PERSPECTIVES FOR BIOMEDICAL SCIENCES: FROM BENCH TO BEDSIDE”; National Laboratory Astana, 2020)
    Введение: В последние годы отмечается тенденция к омоложению хронической ишемии мозга (ХИМ), поэтому важно на основе комплексного клинико-неврологического и клинико-инструмен- тального обследований обеспечить раннюю ...
  • WHOLE-GENOME SEQUENCING AND GENOMIC VARIANT ANALYSIS OF KAZAKH INDIVIDUALS 
    Kairov, Ulykbek; Molkenov, Askhat; Rhie, Arang; Rakhimova, Saule; Yoo, Seong-Keun; Kozhamkulov, Ulan; Sharip, Aigul; Akhmetova, Ainur; Abilmazhinova, Aliya; Zhalbinova, Madina; Yerezhepov, Dauren; Zhabagin, Maxat; Shin, Jeongeon; Kharchenko, Peter; Kim, Jong-Il; Lee, Joseph; Seo, Jeong-Sun; Akilzhanova, Ainur; Zhumadilov, Zhaxybay (International conference "MODERN PERSPECTIVES FOR BIOMEDICAL SCIENCES: FROM BENCH TO BEDSIDE”; National Laboratory Astana, 2020)
    Introduction: Kazakhstan is the multi-ethnic country with the dominant Kazakh ethnic group in the middle of the Eurasian continent. All existing human genetic diversity datasets are only partial representations of worldwide ...
  • A USER-FRIENDLY TOOL FOR SIMPLIFIED GENOMICS DATA MINING FROM LARGE VCF FILES 
    Karabayev, Daniyar; Molkenov, Askhat; Yerulanuly, Kaiyrgali; Daniyarov, Asset; Sharip, Aigul; Seisenova, Ainur; Zhumadilov, Zhaxybay; Kairov, Ulykbek (International conference "MODERN PERSPECTIVES FOR BIOMEDICAL SCIENCES: FROM BENCH TO BEDSIDE”; National Laboratory Astana, 2020)
    Introduction: High-throughput sequencing platforms generate a massive amount of high-dimensional genomic datasets that are available for analysis. Modern and user-friendly bioinformatics tools for analysis and interpretation ...
  • ENGINEERING CHEMOKINE-BASED CCR5 BLOCKERS TO TACKLE INFECTIOUS AND INFLAMMATORY DISEASES 
    Vangelista, Luca (International conference "MODERN PERSPECTIVES FOR BIOMEDICAL SCIENCES: FROM BENCH TO BEDSIDE”; National Laboratory Astana, 2020)
    The C-C chemokine receptor type 5, CCR5, is expressed on various cell types and is involved in a large number of pathophysiological conditions. In recent years, CCR5 gained a huge attention, as it was found to play a ...
  • ISOLATION OF NATURAL REPRESENTATIVES OF CARP LACTOFLORA TO CREATE PATHOGEN CONTROL AGENTS THAT CAN BE ALTERNATIVE TO ANTIBIOTICS 
    Urazova, M.; Zakarya, K.; Sarmurzina, Z.; Bissenova, G.; Abitayeva, G.; Shevtsov, A.; Tekebayeva, Zh.; Tynybayeva, I.; Abzhalelov, A. (International conference "MODERN PERSPECTIVES FOR BIOMEDICAL SCIENCES: FROM BENCH TO BEDSIDE”; National Laboratory Astana, 2020)
    Currently, the microbiome of commercial fish species is being actively studied. In reviews, mainly based on metagenome analysis features and formation of intestinal microflora of various fish species of North America, ...
  • ISOLATION FROM THE KAZAKH TRADITIONAL FOOD PRODUCTS OF A NEW STRAIN OF LACTIC ACID BACTERIA PRODUCING THE HUMAN PLASMINOGEN RECEPTOR 
    Shaikhin, S.; Abitayeva, G.; Abilhadirov, A.; Dossova, A.; Pirmanova, A.; Tynybaeva, I. (International conference "MODERN PERSPECTIVES FOR BIOMEDICAL SCIENCES: FROM BENCH TO BEDSIDE”; National Laboratory Astana, 2020)
    Lactobacillus bacteria are one of the most important groups of the human intestinal microbiota that promote health. Adhesion to host tissues represents a crucial early step in the colonization process of either pathogens ...
  • STRUCTURAL CHANGES IN THE MICROBIOME IN RATS WITH DSS-INDUCED COLITIS 
    Kozhakhmetov, S.; Babenko, D.; Tuyakova, A.; Nurgaziyev, M.; Nurgozhina, A.; Muhanbetganov, N.; Chulenbayeva, L.; Sergazy, S.; Gulyayev, A.; Kushugulova, A. (International conference "MODERN PERSPECTIVES FOR BIOMEDICAL SCIENCES: FROM BENCH TO BEDSIDE”; National Laboratory Astana, 2020)
    Microflora plays a critical role in the initiation and development of inflammatory bowel disease (IBD). There are many facts accumulated about the effect of intestinal dysbiosis on the pathogenesis of Crohn’s disease and ...
  • EFFECT OF MARE’S MILK PREBIOTIC SUPPLEMENTATION ON THE GUT MICROBIOME AND THE IMMUNE SYSTEM DURING AND AFTER ANTIBIOTIC THERAPY 
    Nurgaziyev, M.; Aitenov, Y.; Khassenbekova, Zh.; Akpanova, S.; Rysbekov, K.; Kozhakhmetov, S.; Nurgozhina, A.; Sergazy, Sh.; Chulenbayeva, L.; Ospanova, Zh.; Tuyakova, A.; Mukhambetganov, N.; Sattybayeva, R.; Urazova, S.; Galymgozhina, N.; Gulyaev, A.; Kushugulova, A. (International conference "MODERN PERSPECTIVES FOR BIOMEDICAL SCIENCES: FROM BENCH TO BEDSIDE”; National Laboratory Astana, 2020)
    Antibiotic treatment can severely affect the gut microbiome with short-term and long-term consequences. Probiotic and prebiotic supplements are widely prescribed to modulate the composition and function of the human gut ...
  • CLINICAL EVALUATION OF THE EFFECTIVENESS OF MARE’S MILK IN PSORIASIS 
    Algazina, T.; Yermekbayeva, B.; Batpenova, G.; Kozhakhmetov, S.; Kushugulova, A. (International conference "MODERN PERSPECTIVES FOR BIOMEDICAL SCIENCES: FROM BENCH TO BEDSIDE”; National Laboratory Astana, 2020)
    According to the world health organization, the prevalence of psoriasis in the world is about 2%. However, according to a number of studies, this figure is significantly higher in developed countries and can range from ...
  • Correlation of Serum Biomarkers With the Risk Factors of Colorectal Cancer 
    Akhmaltdinova, L.L.; Avdienko, O.V.; Ibraeva, A.S.; Zhumaliyeva, V.A.; Tauesheva, Z.B. (International conference "MODERN PERSPECTIVES FOR BIOMEDICAL SCIENCES: FROM BENCH TO BEDSIDE”; National Laboratory Astana, 2020)
    Introduction: The search of effective serum biomarkers to diagnose, forecast and evaluate the severity of cancer is a hard and so far unsolved problem. Studying their dynamics, limitations as well as their interaction ...

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