Аннотация:
Haemoperfusion (HP), or blood purification via adsorption, has been introduced
almost at the same time as haemodialysis in 1960s. HP compared to dialysis does not introduce
any substances into the body and only removes the target molecules. Here, we research
properties of activated carbon (AC) materials for HP purposes, which can efficiently adsorb
substances in a broad range of molecular weights. Removing these substances individually,
e.g., by selective antibodies is prohibitively expensive and inefficient due to their short life-time
in blood circulation. And, dialysis and ultrafiltration are unable to remove these low and middle
molecular weight (LMW, MMW) substances efficiently. Here, we assess adsorption of uremic
toxins: p-cresyl sulfate, indoxyl sulfate, and urea.