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Identification of therapeutic targets for chemotherapy-resistant colon cancer stem cells

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dc.contributor.author Francipane, M. G.
dc.contributor.author Bulanin, D.
dc.contributor.author Lagasse, E.
dc.date.accessioned 2016-05-31T03:13:47Z
dc.date.available 2016-05-31T03:13:47Z
dc.date.issued 2016-05
dc.identifier.citation M. G. Francipane, D. Bulanin, and E. Lagasse. 2016. Identification of therapeutic targets for chemotherapy-resistant colon cancer stem cells. Abstract book. 4 th International Scientific Conference “Regenerative medicine & healthy aging”. National Laboratory Astana, Nazarbayev University. http://nur.nu.edu.kz/handle/123456789/1531 ru_RU
dc.identifier.uri http://nur.nu.edu.kz/handle/123456789/1531
dc.description.abstract Current first-line chemotherapy generally consists of cytotoxic agents. While these agents may initially control disease by effectively debulking tumors, the tumors invariably recur due to the ability of cancer stem cells (CSCs) to survive and repopulate the tumor mass. To identify potential molecular targets in 5-fluorouracil (5-FU) refractory colon CSCs, we developed 5-FU resistant cell lines over a period of a year. Here we show that 5-FU maintains colon CSCs in an undifferentiated state in vitro. ru_RU
dc.language.iso en ru_RU
dc.publisher National Laboratory Astana, NAZARBAYEV UNIVERSITY ru_RU
dc.rights Attribution-NonCommercial-ShareAlike 3.0 United States *
dc.rights.uri http://creativecommons.org/licenses/by-nc-sa/3.0/us/ *
dc.subject cancer stem cells ru_RU
dc.subject cancer ru_RU
dc.title Identification of therapeutic targets for chemotherapy-resistant colon cancer stem cells ru_RU
dc.type Abstract ru_RU


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