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Просмотр Abstracts по дате публикации

Просмотр Abstracts по дате публикации

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  • Assessment of nutritional status of elderly and senile age people 
    Doszhanova, G.N.; Abduldayeva, A.A.; Dalenov, E.D. (2016-05)
    Introduction: A healthy nutrition is a predictor of active longevity, contributing to improve the life span and quality of life. Objective: To evaluate the nutritional status of elderly people living in Astana, depending ...
  • Adiponectin plasma levels in patients with age-related dementia 
    Kaiyrlykyzy, A.; Umbayev, B.; Masoud, A.; Shramko, A.; Idrissova, D.; Zhussupova, A.; Alzhanova, D.; Alimbetov, D.; Askarova, S. (2016-05)
    Adiponectin play a significant role in the regulation of type 2 diabetes, obesity, atherosclerosis, non-alcoholic fatty liver disease and neurodegenerative disorders. Evidence suggests that adiponectin may be an independent ...
  • MSCS functionalized with osteophilis polymer enhance compact bone regeneration in osteoporotics rat model in vivo 
    Safarova (Yantsen), Y.; OIzhayev, F.; ldrissova, D.; Umbayev, B.; Murata, H.; Koepsel, R.; Russell, A.; Askarova, Sh. (National Laboratory Astana, NAZARBAYEV UNIVERSITY, 2016-05)
    Undeniable increase in osteoporotic fractures is associated mainly with the global population aging. Age-related alterations shift bone metabolism to induced osteoclastic activity and reduction of osteoblasts that ...
  • c-Met signaling as a promise of targeted therapy in glioblastoma tumor 
    Xie, Y.; Istayeva, Sh.; Tokay, T.; Zhumadilov, Zh.; Chen, Zh. (2016-05)
  • Honey and papaya extract loaded polyurethane based bio-nanofibrous scafford for skin regeneration 
    Jaganathan, S. K. (National Laboratory Astana, NAZARBAYEV UNIVERSITY, 2016-05)
    Skin regeneration is vital for chronic or acute wounds healing. Honey and Carica papaya fruit extract are rich source of various proteins, amino acids, vitamins and essential minerals. These naturally available biomolecules ...
  • Astroprotective potential of extract from limonium gmelinii for stroke therapy 
    Shayakhmetov, Y.; Tsoy, A.; Zhussupova, G.; Askarova, Sh. (2016-05)
    It's known that proinflammatory cytokines, such asTNF-a, produced by injured neurons and infiltrated leukocytes, involved in every aspect of stroke. Cytokines promote activation of astroglia, induce oxidative stress ...
  • Anticancer effects of leech extract on breast cancer cells 
    Murzakhmetova, S.; Janzakova, D.; Mektepbayeva, D. (2016-05)
    Throughout the history of humanity, leech therapy appeared as a procedure in medicine all over the world. The very first use of leech in human treatment was mentioned in Eqypt 3500 years ago. In 2004, Food and Drug ...
  • Effectiveness of pulic screening for glaucoma in republic of Kazakhstan 
    Tashtitova, L.B.; Botabekova, Т.К.; Aldasheva, N.A.; Uteuliyev, E.S. (2016-05)
    In the Republic of Kazakhstan (RK) glaucoma is the second place ranking in the structure of primary disability on eyesight. In 80.2% of cases-these are invalids of the first or second group (Islamova S.E., 2009). In 2010 ...
  • Identification of therapeutic targets for chemotherapy-resistant colon cancer stem cells 
    Francipane, M. G.; Bulanin, D.; Lagasse, E. (National Laboratory Astana, NAZARBAYEV UNIVERSITY, 2016-05)
    Current first-line chemotherapy generally consists of cytotoxic agents. While these agents may initially control disease by effectively debulking tumors, the tumors invariably recur due to the ability of cancer stem cells ...
  • Removal of low and middle molecular weight toxins by activated carbon materials 
    Akhmetova, A.; Howell, C.; Jandosov, J.; Baimenov, A.; Mansurov, Z.; Nurgozhin, T.; Mikhalovsky, S. (National Laboratory Astana, NAZARBAYEV UNIVERSITY, 2016-05)
    Haemoperfusion (HP), or blood purification via adsorption, has been introduced almost at the same time as haemodialysis in 1960s. HP compared to dialysis does not introduce any substances into the body and only removes ...
  • Apolipoprotein E genetic variation and statin therapy appointment 
    Kassenova, A.; Kossumov, A.; Nurgozhin, T.; Supiyev, A. (2016-05)
    Dyslipidemia is an important risk factor for cardiovascular disease due to the significant influence of cholesterol on atherosclerosis. Several genetic variants in genes related with triglyceride (TG) metabolism has been ...
  • Generation of hepatocyte-like cells from human pluripotent stem cells 
    Sekenova, A.; Kumasheva, V.; Li, Ye.; Baidosova, Sh.; Ogay, V. (National Laboratory Astana, NAZARBAYEV UNIVERSITY, 2016-05)
    The demand for donor livers in transplantation medicine continues to increase every year with the difficulties in finding compatible human hepatocytes. Therefore, generation of patient specific human hepatocytes from ...
  • Isolation and enrichment of rat bone marrow mesenchymal stem cells 
    Baidosova, S.; Kumasheva, V.; Kerimbayev, T.; Aleynikov, V.; Aldiyarova, N.; Ogay, Vyacheslav (National Laboratory Astana, NAZARBAYEV UNIVERSITY, 2016-05)
    Mesenchymal stem cells (MSCs) are a promising tool for cell therapy, because of their specific characteristics, which mimic partially those of embryonic stem cells, but with some advantages in terms of availability, ...
  • Morphometric characteristics of cancer cells grown in embryonic microenvironment and under antiviral treatment 
    Shaimerdenova, M.; Karapina, O.; Mektepbayeva, D.; Akilbekova, D. (National Laboratory Astana, NAZARBAYEV UNIVERSITY, 2016-05)
    Aggressive cancer cells express markers of multipotent stem cells and tightly interconnect with its surrounding microenvironment, by which the differential plasticity of cancer cells and also its carcinogenicity is ...
  • A targeted sequencing reveal overlapping pattern of genetic variants in patients with cardiomyopathy with cardiac arrhythmias in Kazakhstan 
    Akilzhanova, A.; Guelly, Ch.; Abilova, Zh.; Rakhimova, S.; Akhmetova, A.; Kairov, U.; Nuralinov, O.; Rashbayeva, G.; Trajanoski, S.; Zhumadilov, Zh.; Bebosynova, M. (2016-05)
    Ventricular tachycardia (VT) is a common symptom in cardiac disorders of different etiology. Abnormalities of ion channels are attributed to mutations in the genes encoding the channel protein and cause altered function ...
  • Glial cells and their molecules in nerve regeneration 
    Riethmacher, D. (2016-05)
    Peripheral nerve injury has many causes ranging from traumatic damage to metabolic disturbances (e.g.in diabetes mellitus). The primary pathology can affect axons (nerve transection) or Schwann cells, and their interdependence ...
  • Antioxidant properties of grape polyphenol concentrate from Kazakhstan region 
    Yermekbayeva, B.; Shulgau, Z.; Sergazy, Sh.; Kabdullina, A.; Khassenbekova, Zh.; Tritek, V.; Abuova, G.; Zhaugasheva, S.; Gulyayev, A.; Nurgozhin, T. (2016-05)
    It is believed that the antioxidant effects are widespread among plant polyphenols. Antioxidant effect is associated with main biological activities of polyphenols. Objective. To describe the antioxidant effect of grape ...
  • Protocol optimization for abtaining lyophilized human amniotic membrane extract 
    Shramko, A.; Umbayev, В.; Olzhayev, R.; Idrissova, D.; Masoud, A.; Sadyrbekov, D.; Askarova, Sh. (National Laboratory Astana, NAZARBAYEV UNIVERSITY, 2016-05)
    The amniotic membrane (AM) is the inner amniotic fluid-filled membrane which forms a cavity around the embryo. AM has long been used in the treatment of venous ulcers and burns. Freshly extracted AM has been shown to ...
  • Alterations of oncogenes expression in human NK cells in cancer patients 
    Amirbekov, A.; Eraliyeva, L.; Zakiryanova, G. (2016-05)
    C-kit/SCF signaling play a key role in regulating NK cell homeostasis, maturation, proliferation and cytotoxicity. C-kit-deficiency in NK results in significant reduction of their, suggesting imperative role fore-kit ...
  • Results of the study of biological subtypes of breast cancer 
    Tailakov, B.B.; Tuleutaev, M.E.; Pirozhenko, O.P.; Gubskaya, E.B.; Orazbekov, B.S.; Balhozhaeva, A.A.; Zhukov, Y.; Rutzhanuly, I.R.; Omarov, M.H.; Makis, R.T.; Tusupbekov, E.H.; Ermagambetova, A.T. (National Laboratory Astana, NAZARBAYEV UNIVERSITY, 2016-05)
    Identification of biological subtypes of breast cancer using immunohistochemical tumor markers: ER and RP receptor, Ki67, Her-2 / neu is a modern criterion for the development of optimal therapies for the breast cancer.

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