Browsing Research Institute of Biosensors Technology by Author "3a1f1c02-93bf-4ed8-b626-f92424356986"

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Characterization of DNA ADP-ribosyltransferase activities of PARP2 and PARP3: new insights into DNA ADP-ribosylation

Zarkovic, Gabriella; Belousova, Ekaterina; Talhaoui, Ibtissam; Saint-Pierre, Christine; Kutuzov, Mikhail M.; Matkarimov, Bakhyt; Biard, Denis; Gasparutto, Didier; Lavrik, Olga I.; Ishchenko, Alexander A. (Oxford University Press, 2018-01)

Poly(ADP-ribose) polymerases (PARPs) act as DNA break sensors and catalyze the synthesis of polymers of ADP-ribose (PAR) covalently attached to acceptor proteins at DNA damage sites. It has been demonstrated that both ...