Browsing Research Institute of Bioengineering, Regenerative Medicine and Neurophysiology by Author "Baltrusch, Simone"

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Reduced adolescent-age spatial learning ability associated with elevated juvenile-age superoxide levels in complex I mouse mutants

Mayer, Johannes; Reichart, Gesine; Tokay, Tursonjan; Lange, Falko; Baltrusch, Simone; Junghanss, Christian; Wolkenhauer, Olaf; Jaster, Robert; Kunz, Manfred; Tiedge, Markus; Ibrahim, Saleh; Fuellen, Georg; Köhling, Rüdiger (PLOS ONE:Open Access journal, 2015-04-15)

Large-scale, heteroplasmic and generally pathogenic mtDNA defects (as induced by defective mitochondrial DNA polymerase, clonal mutations or DNA deletions) are known to negatively impact on life span and can result in ...