Browsing 02.National Laboratory Astana by Author "Kushugulova, A.R."

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Erythrocyte ghosts` influence on the phenotypic plasticity of macrophage

Khassenbekova, Zh.; Berikkhanova, K.; Gulyayev, A.; Sergazy, Sh.; Yermekbayeva, В.; Kushugulova, A.R.; Omarova, D.; Akhmetova, A.; Nurgozhin, T.; Zhumadilov, Zh. (2016-05)

Correction of phenotypic plasticity of macrophages for reprogramming inflammatory response is of great interest to modern medicine. To date, there are lots of factors, which can alter macrophages' phenotype to M1 or M2. ...
Study the effect of gene polymorphism contribution of statin biotransformation and lipid metabolism for parameters of statin efficacy. Recruiting

Kozhakhmetov, S.S.; Kushugulova, A.R.; Kakimova, A.B.; Saduakhassova, S.A.; Urasova, M.S.; Khassenbekova, Zh.R.; Kozhakhmetova, S.S.; Kazhybayev, A.K.; Urazbayeva, G.S.; Tuleutayeva, G.K.; Ongarbayeva, A.E.; Beysembayeva, S.Ch.; Nurgozhin, T.S.; Zhumadilov, Zh. (National Laboratory Astana, Nazarbayev University 2016, 2016-05-11)

Rosuvastatin is high-performance hydroxymethylglutaryl coenzyme A (HMG-CoA) reductase, which commonly used in the treatment of hyperlipidemia. It significantly reduces levels of LDL, which accompanied by a moderate increase ...