NUR Home
→
02.National Laboratory Astana
→
Browsing 02.National Laboratory Astana by Title

Browsing 02.National Laboratory Astana by Title

Now showing items 3-22 of 821

Aberrant base excision repair pathway of oxidatively damaged DNA: Implications for degenerative diseases

Talhaoui, Ibtissam; Matkarimov, Bakhyt T.; Tchenio, Thierry; Zharkov, Dmitry O.; Saparbaev, Murat K. (Free Radical Biology and Medicine, 2017-06-01)

Abstract In cellular organisms composition of DNA is constrained to only four nucleobases A, G, T and C, except for minor DNA base modifications such as methylation which serves for defence against foreign DNA or gene ...
Aberrant DNA glycosylase-initiated repair pathway of free radicals induced DNA damage: implications for age-related diseases and natural aging

Matkarimov, B.; Saparbaev, M. (Biopolymers and Cell. doi: http://dx.doi.org/10.7124/bc.000943, 2017)

Aerobic cellular respiration generates reactive oxygen species (ROS), which can damage macro-molecules including lipids, proteins and DNA. It was proposed that aging is a consequence of accumulation of naturally occurring ...
Aberrant repair initiated by mismatch-specific thymine-DNA glycosylases provides a mechanism for the mutational bias observed in CpG islands

Talhaoui, Ibtissam; Couve, Sophie; Gros, Laurent; Ishchenko, Alexander A.; Matkarimov, Bakhyt; Saparbaev, Murat K. (Nucleic Acids Research, 2014-04-01)

The human thymine-DNA glycosylase (TDG) initiates the base excision repair (BER) pathway to remove spontaneous and induced DNA base damage. It was first biochemically characterized for its ability to remove T mispaired ...
Aberrant repair initiated by the adenine-DNA glycosylase does not play a role in UV-induced mutagenesis in Escherichia coli

Zutterling, Caroline; Mursalimov, Aibek; alhaoui, Ibtissam; Koshenov, Zhanat; Akishev, Zhiger; Bissenbaev, Amangeldy K.; Mazon, Gerard; Geacintov, Nicolas E.; Gasparutto, Didier; Groisman, Regina; Zharkov, Dmitry O.; Matkarimov, Bakhyt T.; Saparbaev, Murat (BIOCHEMISTRY, BIOPHYSICS AND MOLECULAR BIOLOGY, 2018-12-15)

DNA repair is essential to counteract damage to DNA induced by endo- and exogenous factors, to maintain genome stability. However, challenges to the faithful discrimination between damaged and non-damaged DNA strands ...
Abstract Book of The 8th International Conference on Nanomaterials and Advanced Energy Storage Systems

Unknown author (The 8th International Conference on Nanomaterials and Advanced Energy Storage Systems; Nazarbayev University; National Laboratory Astana; Institute of Batteries, 2020-08)

The INESS 2020 topics covered the following and related areas: advanced nanomaterials for energy application, advanced energy storage, conversion and saving systems, materials for electrochemical sensor and electroanalytical ...
Acoustoelectric properties of graphene under the influence of saw and external electric field

Insepov, Z.; Tynyshtykbayev, Kurbangali B.; Kononenko, Oleg V.; Roshchupkin, Dmitry V. (Nazarbayev University, NURIS, Institute of Microelectronics Technology and High Purity Materials, 2015)

The effect of SAW on the electrical properties of the few-layer (2-3 layers) graphene is studied. Under the influence of SAW the appearence of acoustoelectric current IAEC in graphene is observed. The sign and magnitude ...
ACTIVATED CARBON/PECTIN COMPOSITE ENTEROSORBENT FOR HUMAN PROTECTION FROM INTOXICATION WITH XENOBIOTICS PB(II) AND SODIUM DICLOFENAC

Jandosov, Jakpar; Alavijeh, Mo; Sultakhan, Shynggyskhan; Baimenov, Alzhan; Bernardo, Maria; Sakipova, Zuriyadda; Azat, Seytkhan; Lyubchyk, Svitlana; Zhylybayeva, Nurzhamal; Naurzbayeva, Gulmira; Mansurov, Zulkhair; Mikhalovsky, Sergey; Berillo, Dmitriy (Molecules, 2022)

The use of enterosorbents—materials which can be administered orally and eliminate toxic substances from the gastrointestinal tract (GIT) by sorption—offers an attractive complementary protection of humans against acute ...
Activation of cell ageing pathways with novel small molecules for cancer treatment

Masoud, A.; Brook, A.; Davis, T.; Umbayev, B.; Tsoy, A.; Askarova, Sh.; Kipling, D.; Alimbetov, D. (National Laboratory Astana, Nazarbayev University, 2017-09-15)
A design for large-area fast photo-detectors with transmission-line readout and waveform sampling

Adams, B.; Anderson, J. T.; Attenkofer, K.; Bogdan, M.; Byrum, K.; Drake, G.; Insepov, Z. (In Real Time Conference, 2009. RT'09. 16th IEEE-NPSS (pp. 49-61). IEEE., 2009)

We present a preliminary design and the results of simulation for a photo-detector module to be used in applications requiring the coverage of areas of many square meters with time resolutions less than 10 picoseconds and ...
Adiponectin plasma levels in patients with age-related dementia

Kaiyrlykyzy, A.; Umbayev, B.; Masoud, A.; Shramko, A.; Idrissova, D.; Zhussupova, A.; Alzhanova, D.; Alimbetov, D.; Askarova, S. (2016-05)

Adiponectin play a significant role in the regulation of type 2 diabetes, obesity, atherosclerosis, non-alcoholic fatty liver disease and neurodegenerative disorders. Evidence suggests that adiponectin may be an independent ...
Adipose-derived perivascular stem cell as a source for cell therapy

Ogay, V. (2016-05)

Perivascular stem cells (PSCs) have been isolated from several organs and tissues, including adipose tissue. They have unique features resembling both pericytes and mesenchymal stem cells (MSCs). PSCs as MSCs are capable ...
Adipose-derived perivascular stem cells promote sensorimotor recovery after ischemic stroke in rats

Ogay, Vyacheslav; Kumasheva, Venera; Baidosova, Sholpan; Li, Yelena; Shpekov, Azat; Makhambetov, Yerbol; Kaliyev, Assylbek; Zhetpisbayev, Berik; Olzhayev, Farkhad; Ramankulov, Yerlan (Journal of Biotechnology, 2017-08-30)

In this study, we test a novel hypothesis that treatment of stroke with adipose-derived perivascular stem cells (PSCs) promote sensorimotor recovery after stroke in rats. Rat PSCs were isolated from subcutaneous adipose ...
ADSORPTION AND DISPLACEMENT OF METHANE IN GRAPHENE-BASED MICROSTRUCTURES: INSIGHT FROM MOLECULAR SIMULATIONS

Bekeshov, Dias; Ashimov, Sultan; Wang, Yanwei; Wang, Lei (National Laboratory Astana, 2022-08)

Shale gas and coalbed methane are alternative energy sources that partly or even mainly consist of methane stored in an adsorbed state in pores of organic-rich rock and coal seams. This study employed a combination of Grand ...
Adsorption arsenite from aqueous solutions by Cu/CuO loaded composite track-etched membranes

Mashentseva, Anastassiya; Khassen, Tomiris; Zhumazhanova, Ainash; Zheltov, Dmitriy; Russakova, Alyona; Rakisheva, Saniya; Altynbayeva, Liliya; Aimanova, Nurgulim (The 8th International Conference on Nanomaterials and Advanced Energy Storage Systems; Nazarbayev University; National Laboratory Astana; Institute of Batteries, 2020-08)

Nanoscale structures of copper and its oxides are widely used in heterogeneous catalysis and demonstrate improved properties compared to bulk analogues [1]. Previously, we demonstrated the high potential of composite ...
ADSORPTION OF POLYETHENE GLYCOL AND PROPYLENE GLYCOL ONTO THE MODIFIED GLASS MICROSPHERES

Amerkhanova Shamshiya (National Laboratory Astana, 2022-08)

Since polyethene glycol (PEG) and other derivatives of ethylene oxides are contained in the composition of medicinal and detergents, their large volumes enter water bodies. However, the issue of removing PEG and other ...
Advanced Functional Nanomaterials for Photocatalytic Water Splitting

Nuraje, Nurxat (The 8th International Conference on Nanomaterials and Advanced Energy Storage Systems; Nazarbayev University; National Laboratory Astana; Institute of Batteries, 2020-08)

Through mimicking Nature, unique assembled nanostructures can be designed and fabricated to improve certain properties of materials and device performance for targeted applications. In this presentation, we discuss the ...
Advanced Surface Polishing For Accelerator Technology Using Ion Beams

Insepov, Z.; Norem, J.; Hassanein, A.; Wu, A. T. (American Institute of Physics, 2009-03)

Surface erosion problems are common in the development of TeV accelerators, fusion and fission reactors, semiconductor, optical and magnetic storage devices, and Extreme Ultra-Violet (EUV) lithography devices. We have ...
A General Model of Vacuum Arcs in Linacs

Norem, J.; Insepov, Z. (Proceedings of NAPAC2016, Chicago, IL, USA, 2017-01)

We are developing a general model of breakdown and gradient limits that applies to accelerators, along with other high field applications such as power grids and laser ablation. We have considered connections with failure ...
AGE REPROGRAMMING AND EPIGENETIC REJUVENATION

Kulaissova, A.; Singh, Prim B. (International conference "MODERN PERSPECTIVES FOR BIOMEDICAL SCIENCES: FROM BENCH TO BEDSIDE”; National Laboratory Astana, 2020)

Introduction: Age reprogramming represents a novel method for generating patient-specific tissues for transplantation. It bypasses the de-differentiation/re-differentiation cycle that is characteristic of the induced ...
Ag:TiO2 plasmonic nanocomposite films obtained by RF magnetron co-sputtering

Mukhametkarimov, Yerzhan; Mikhailova, Svetlana; Prikhodko, Oleg; Dauitkhan, Kuanysh; Puzikova, Darya; Doseke, Ulantai (The 8th International Conference on Nanomaterials and Advanced Energy Storage Systems; Nazarbayev University; National Laboratory Astana; Institute of Batteries, 2020-08)

It is known that TiO2 is a wide-gap semiconductor, which due to its low cost and photocatalytic properties has found great application in purification of water and organic pollution, as well as solar energy [1]. To expand ...