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Browsing Articles by Subject "gene expression"

Now showing items 1-3 of 3

Deletion of HP1γ in cardiac myocytes afects H4K20me3 levels but does not impact cardiac growth

El‑Nachef, Danny; Fang, Chen; Kajimoto, Hidemi; Brown, Jeremy P.; Singh, Prim B.; MacLellan, W. Robb (Epigenetics Chromatin, 2018-04-18)

Heterochromatin, which is formed when tri-methyl lysine 9 of histone H3 (H3K9me3) is bound by heterochromatin 1 proteins (HP1s), plays an important role in differentiation and senescence by silencing cell cycle genes. ...
Lack of Clinical Manifestations in Asymptomatic Dengue Infection Is Attributed to Broad Down-Regulation and Selective Up-Regulation of Host Defence Response Genes

Yeo, Adeline; Azhar, Nur Atiqah; Yeow, Wanyi; Talbot Jr., C. Conover; Asif Khan, Mohammad; Shankar, Esaki M.; Rathakrishnan, Anusyah; Azizan, Azliyati; Wang, Seok Mui; Kim Lee, Siew; Yik Fong, Mun Yik; Manikam, Rishya; Devi Sekaran, Shamala (PLOS ONE:Open Access journal, 2014-04)

Dengue represents one of the most serious life-threatening vector-borne infectious diseases that afflicts approximately 50 million people across the globe annually. Whilst symptomatic infections are frequently reported, ...
Tumor antigens as proteogenomic biomarkers in invasive ductal carcinomas

Olsen, Lars Rønn; Campos, Benito; Winther, Ole; Sgroi, Dennis C.; Karger, Barry L.; Brusic, Vladimir (BMC Medical Genomics, 2014-12-08)

Background: The majority of genetic biomarkers for human cancers are defined by statistical screening of high-throughput genomics data. While a large number of genetic biomarkers have been proposed for diagnostic and ...