Background and objectives: Skin grafting is a method usually used in reconstructive surgery
to accelerate skin regeneration. This method results frequently in unexpected scar formations.
We previously showed that cutaneous ...
Myocardial infarction causes cardiac tissue damage and the release of damage-associated molecular patterns leads to activation of the immune system, production of inflammatory mediators, and migration of various cells to ...
Collagens act as cellular scaffolds in extracellular matrixes, and their breakdown products may also have important biological functions. We hypothesize that collagen dipeptide Pro-Hyp induces favorable healing activities ...
Wound healing is a complex physiological reaction in our body to tissue injury that can lead to the impairment of the original organ functions depending on the area of tissue injury. Many cell types participate in the wound ...
Skin wounds greatly affect the global healthcare system, creating a substantial burden on the economy and society. Moreover, the situation is exacerbated by low healing rates, which in fact are overestimated in reports. ...
Kim, Yevgeniy; Nurakhayev, Sanzhar; Nurkesh, Ayan; Zharkinbekov, Zharylkasyn; Saparov, Arman(International Journal of Molecular Sciences, 2021-03-08)
Cardiovascular disease is the leading cause of mortality and morbidity around the globe,
creating a substantial socio-economic burden as a result. Myocardial infarction is a significant contributor to the detrimental ...
Mesenchymal stem cells (MSCs) have great potential to differentiate into various types of cells, including but not limited to, adipocytes, chondrocytes and osteoblasts. In addition to their progenitor characteristics, MSCs ...
Negative pressure wound therapy (NPWT) has been commonly used over the years for
a wide range of chronic/refractory lesions. Alternatively, autologous micrografting technology is
recently becoming a powerful modality for ...
Ischemic heart disease and myocardial infarction remain leading causes of mortality worldwide. Existing myocardial infarction treatments are incapable of fully repairing and regenerating the infarcted myocardium. Stem cell ...
Bioengineered materials are widely utilized due to their biocompatibility and
degradability, as well as their moisturizing and antibacterial properties. One field of
their application in medicine is to treat wounds by ...
Jimi, Shiro; Jaguparov, Alexandr; Nurkesh, Ayan; Sultankulov, Bolat; Saparov, Arman(Frontiers in Bioengineering and Biotechnology, 2020-04)
Growth factors and cytokines that are secreted by cells play a crucial role in the complex physiological reaction to tissue injury. The ability to spatially and temporally control their actions to maximize regenerative ...
Despite their conventional and widespread use, oral and intravenous routes of drug administration face several limitations. In particular, orally administered drugs undergo enzymatic degradation in the gastrointestinal ...