Browsing Articles by Author "8c994a77-5c21-45af-b5a7-24e6c55fc868"

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Carrier frequency of HLA-DQB1*02 allele in patients affected with celiac disease: A systematic review assessing the potential rationale of a targeted allelic genotyping as a first-line screening

Poddighe, Dimitri; Rebuffi, Chiara; De Silvestri, Annalisa; Capittini, Cristina (Baishideng Publishing Group, 2020-03-28)

The final output of this systematic search in the medical literature consisted of 38 studies providing the appropriate HLA-DQB1 genotype information of the respective CD population. According to this systematic review, ...
Relevance of HLA-DQB1*02 Allele in the Genetic Predisposition of Children with Celiac Disease: Additional Cues from a Meta-Analysis

Capittini, Cristina; De Silvestri, Annalisa; Rebuffi, Chiara; Tinelli, Carmine; Poddighe, Dimitri (MDPI, 2019-05)

Background and Objectives: Celiac disease (CD) is a multifactorial immune-mediated disorder, triggered by the ingestion of gluten in genetically-predisposed subjects carrying MHC-DQ2 and -DQ8 heterodimers, which are encoded ...