Nazarbayev University Repository
http://nur.nu.edu.kz:80
The DSpace digital repository system captures, stores, indexes, preserves, and distributes digital research material.2024-03-04T03:13:58ZANALYSIS OF INTERFERENCE IN LFM RADAR DETECTION AND IMAGING IN A MULTI-RADAR ENVIRONMENT
http://nur.nu.edu.kz:80/handle/123456789/7590
ANALYSIS OF INTERFERENCE IN LFM RADAR DETECTION AND IMAGING IN A MULTI-RADAR ENVIRONMENT
Nwigbo, Suanu
Because of the growing use of radio detection and ranging (radar) systems in multiple application sectors, the radars have to be operated on the same or adjacent frequency resources. This frequency overlap can cause interference and impacts the performance of the victim radar. Besides unintended interferences, there could also be intentional interferences. The interference can cause a reduction in the signal-to-noise ratio, introduce ghost targets, and lead to poor detection capabilities of the radar as well as false detections. Thus, interference effects should be compensated to operate the radar in a safe and secure environment.
In this thesis, different types of interference and their impact on traditional linear frequency modulation (LFM) based radio detection and ranging (radar) are investigated through numerical simulation and electronic radar-based experiments. The work has been extended to investigate the imaging of radar-detected objects with the help of the back-projection technique.
In the simulation environment, a multi-radar environment has been created to investigate the effect of external interference radar on the victim radar. Different types of interference waveforms such as LFM, triangular and pulsed waveforms are being considered. It is found that the LFM-based waveform suffers from coherent LFM interference, which can result in the appearance of ghost targets on the range profile. Whereas, non-coherent types of interference increase the noise level, reducing the signal-to-noise ratio, thus adversely impacting the detection accuracy. Thus, a random hopping LFM-based waveform as an alternative to the LFM-based waveform has been proposed as a robust waveform to mitigate interference in a multi-radar environment.
Experimental work with an mm-wave (77GHz-81GHz) radar sensor for detecting targets has been performed, and radar performance metrics such as range and range resolution have been evaluated with the theoretical values.
Through the back-projection algorithm, the imaging of the detected objects has been obtained. Through extensive iteration, it is found that the back-projection with weighting function provides enhanced resolution.
2023-04-01T00:00:00ZНА ПУТИ К БОЛЕЕ СИЛЬНОЙ И УСТОЙЧИВОЙ БИБЛИОТЕЧНОЙ СФЕРЕ В АЗИИ И ОКЕАНИИ: ОБ УЧАСТИИ В СЕМИНАРЕ ИФЛА
http://nur.nu.edu.kz:80/handle/123456789/7589
НА ПУТИ К БОЛЕЕ СИЛЬНОЙ И УСТОЙЧИВОЙ БИБЛИОТЕЧНОЙ СФЕРЕ В АЗИИ И ОКЕАНИИ: ОБ УЧАСТИИ В СЕМИНАРЕ ИФЛА
Лапо, Пётр
С 14 – 16 ноября 2022 года от имени Ассоциации библиотек высших учебных заведений Республики Казахстан (АБВК), являющейся членом Международной федерации библиотечных ассоциаций и учреждений (ИФЛА), я принял участие в семинаре, организованном комитетом регионального отделения ИФЛА по Азии и Океании, Тайской библиотечной ассоциацией и Национальной библиотекой Таиланда при финансовой поддержке центрального офиса ИФЛА и проведенном в Национальной библиотеке Таиланда (г. Бангкок)...
2022-11-01T00:00:00ZО ДЕЯТЕЛЬНОСТИ АССОЦИАЦИИ ВУЗОВСКИХ БИБЛИОТЕК КАЗАХСТАНА
http://nur.nu.edu.kz:80/handle/123456789/7588
О ДЕЯТЕЛЬНОСТИ АССОЦИАЦИИ ВУЗОВСКИХ БИБЛИОТЕК КАЗАХСТАНА
Лапо, Петр
Общественное объединение «Ассоциация библиотек высших учебных заведений Республики Казахстан» (на государственном языке «Жоғары оқу орындары кітапханаларының қауымдастығы» қоғамдық бірлестігі) было создано в 2012году, и в качестве места размещения его головного офиса был определен Таразский региональный университет имени М.Х. Дулати, директор Библиотечно-информационного центра которого, Иржанова Гульжан Дженисбеккызы, внесла и вносит большой вклад в создание и становление данного общественного объединения...
2023-01-01T00:00:00ZО МЕЖДУНАРОДНЫХ АСПЕКТАХ ДЕЯТЕЛЬНОСТИ НАЦИОНАЛЬНЫХ БИБЛИОТЕК И БИБЛИОТЕЧНЫХ АССОЦИАЦИЙ В ЦЕНТРАЛЬНОЙ АЗИИ
http://nur.nu.edu.kz:80/handle/123456789/7587
О МЕЖДУНАРОДНЫХ АСПЕКТАХ ДЕЯТЕЛЬНОСТИ НАЦИОНАЛЬНЫХ БИБЛИОТЕК И БИБЛИОТЕЧНЫХ АССОЦИАЦИЙ В ЦЕНТРАЛЬНОЙ АЗИИ
Лапо, Пётр
В статье анализируются текущее состояние и перспективы развития организационной структуры региональной библиотечной системы Центральной Азии для получения синергетического эффекта по реализации международной деятельности библиотек региона, прежде всего, в рамках инициированных Международной федерацией библиотечных ассоциаций и учреждений (ИФЛА) глобальных проектов. Системная, планомерная и слаженная работа на всех уровнях региональной библиотечной системы рассматривается как главное условие эффективной международной деятельности библиотек Центральной Азии
2023-05-01T00:00:00ZHEART SOUND CLASSIFICATION VIA VISION TRANSFORMER MODELS
http://nur.nu.edu.kz:80/handle/123456789/7586
HEART SOUND CLASSIFICATION VIA VISION TRANSFORMER MODELS
Adilkhanuly, Zhanat
The automatic heart sound classification is an integral part of the early diagnosis
of cardiovascular diseases(CVDs). Even though advances in medical technologies
allow us to diagnose many CVDs, it remains one of the leading causes of death
worldwide due to its absence of symptoms at the initial stages. Thus, there is a huge
demand to develop other methods of identifying heart sound abnormalities that are
less expensive, simple, and applicable. Several audio feature extraction methods, in
combination with classification models, have been developed over time. However,
existing feature extraction methods are sensitive to noise, which negatively impacts
the performance of the heart sound classification model. In addition, there is a strong
need to develop models more sensitive to heart sound abnormalities in patients. In this
work, we address the limitations of extracted features by using spectrogram images
that are taken from Discrete Fourier Transform, and introducing them to Vision
Transformer Model. Results of our experiments on the benchmark of PhysioNet Heart
Sound Dataset show that the proposed method outperforms existing methodologies
with an accuracy of 0.925 and with a sensitivity score of 0.955
2023-11-23T00:00:00ZTHE AXL INHIBITOR TP-0903 AND ARTESUNATE SYNERGISE TO INDUCE REACTIVE OXYGEN SPECIES, DNA DAMAGE AND APOPTOSIS IN TRIPLE NEGATIVE BREAST CANCER CELLS
http://nur.nu.edu.kz:80/handle/123456789/7585
THE AXL INHIBITOR TP-0903 AND ARTESUNATE SYNERGISE TO INDUCE REACTIVE OXYGEN SPECIES, DNA DAMAGE AND APOPTOSIS IN TRIPLE NEGATIVE BREAST CANCER CELLS
Terragno, Mirko
Triple Negative Breast Cancer (TNBC) is an aggressive, often rapidly growing form of breast cancer. TNBC usually displays a basal molecular phenotype that associates with epithelial mesenchymal transition (EMT), a cellular program that confers chemoresistance and metastasis. Approximately 56% of TNBC cases show a basal-like gene expression profile and roughly 46% of TNBC patients have distant metastasis. In general, the absence of molecular targets in TNBC is the main obstacle for the development of an effective therapy. For example, TNBC does not respond to endocrine and anti-human epidermal receptor (HER2) treatments as it does not express estrogen and progesterone receptors (ESR/PgR) and human epidermal receptor 2 (HER2). In addition, though initially TNBC is more responsive to cytotoxic drugs compared to other subtypes, TNBC presents a higher relapse rate. Therefore, new anti-TNBC treatment strategies are urgently needed. Drug combination therapy for TNBC could rely on protocols whereby EMT reversal sensitizes TNBC to anti-cancer compounds that are effective against epithelial tumors. Recently, the anti-malaria compound Artesunate (ART) has been shown to exert cytotoxicity in breast cancer by generating reactive oxygen species (ROS) and DNA double strand breaks (DSBs). However, the effect was more pronounced in tumors of epithelial than mesenchymal origin. In this project, the hypothesis was to verify whether EMT inhibition could sensitize TNBC cell lines to ART cytotoxicity. To address this, two aims were pursued. Aim 1 verified whether receptor tyrosine kinase (RTK) AXL inhibitors TP-0903/R428 and AXL/ZEB1 knockdown sensitised TNBC cell lines to ART-generated ROS, DNA damage and apoptosis. Aim 2 was to test whether TP-0903 and AXL/ZEB1 knockout in TNBC cell lines suppressed expression of superoxide dismutase 1/2 (SOD1/2), glutathione peroxidase 8 (GPX8) and catalase (CAT)...
2024-01-01T00:00:00Z