Browsing by Author "Yantsen, Y."

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Mesenchymal stem cells and osteophilic polymer as promising agents in bone regeneration

Yantsen, Y.; Idrissova, D.; Olzhayev, F.; Umbayev, B.; Murata, H.; Russell, A.; Askarova, Sh. (Center for Life Sciences, Nazarbayev University, 2014)

Mesenchymal stem cells (MSCs) are an attractive stem cell source for transplantation. MSCs can easily differentiate into osteoblasts and increase in osteoblast number will have positive effect on the bone regeneration in ...
Polymer coating enhances affinity of bone marrow-derived MSCS to bone

Yantsen, Y.; Askarova, Sholpan; Adambekov, S.; Murata, H.; Andersen, J.; D’Souza, S.; Edington, C.; Koepsel, R.; Russell, A. (Nazarbayev University, 2013)

The polymer coated cells were shown to be stably attached to bone fragments for at least 2 hours, confirming the bone targeting potential of the polymer. Our next step will be to test this approach in rat model of osteoporosis ...