Almost one third of the world's population is infected with Mycobacterium tuberculosis
(MTB) and only 10% of them will develop any active form of the disease. TB is second (1s t is HIV/AIDS)
greatest killer worldwide due ...
Ventricular tachycardia (VT) is a common symptom in cardiac disorders of
different etiology. Abnormalities of ion channels are attributed to mutations in the genes
encoding the channel protein and cause altered function ...
Abilmazhinova, A.; Zhabagin, M.; Rakhimova, S.; Bakhtin, M.; Kazymbet, P.; Akilzhanova, A.; Zhumadilov, Z.(Nazarbayev University, 2014)
Taking into account the fact that Kazakhstan is one of the world's leaders in uranium mining, and given the extent of the damage suffered as a result of the work on the Semipalatinsk nuclear test site, the general background ...
We designed a case-control study to examine demographic, clinical, social and cultural factors associated with tuberculosis in four regions of Kazakhstan. Cases included persons identified by the national tuberculosis ...
Zhalbinova, M.; Rakhimova, S.; Bekbosynova, M.; Myrzakhmetova, Sh.; Akilzhanova, A.(National Laboratory Astana, NAZARBAYEV UNIVERSITY, 2016-05)
Warfarin is an oral anticoagulant which is popular in cardiology for the prevention
and treatment of thromboembolic events in patients with deep vein thrombosis. Patients usually
treated according to the clinical data. ...
In this study combined design was used, which included: 1) Case-control study; 2) Molecular epidemiological study; and 3) Study of human genetic susceptibility to tuberculosis.This work is the first case-control study in ...
Akilzhanova, A.; Guelly, C.; Abilova, Z. M.; Rakhimova, S.; Nuralinov, O. M.; Abdrakhmanov, A. C.; Bekbosynova, M. S.(Nazarbayev University, 2014)
The human ryanodine receptor 2 (RYR2) is one of the key players tightly regulating
calcium efflux from the sarcoplasmic reticulum to the cytosol and found frequently mutated (<60%) in
context of catecholaminergic polymorphic ...
Rakhimova, S.; Kairov, U.; Molkenov, A.; Zhukov, Y.; Omarov, M.; Popova, M.; Zhumadilov, Zh.; Akilzhanova, A.(National Laboratory Astana, Nazarbayev University 2016, 2016-05-11)
Esophageal cancer is the eighth most common cancer in the world and the highest in Eastern Asia. The incidence rate in Kazakhstan is 10.1: 100 000. Esophageal squamous cell carcinoma (ESCC) is the dominant histological ...
The project is aimed to create the prerequisites for a personalized approach to the diagnosis
and treatment of tuberculosis (TB) by identifying and comparing the whole genome sequences of
M.tuberculosis strains isolated ...