Browsing by Author "Abetov, Danysh"

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Biomarkers and signaling pathways of colorectal cancer stem cells

Abetov, Danysh; Mustapova, Zhanar; Saliev, Timur; Bulanin, Denis (Tumor Biology, 2015-03-01)

The progression of colorectal cancer is commonly characterized by accumulation of genetic or epigenetic abnormalities, altering regulation of gene expression as well as normal protein structures and functions. Nonetheless, ...
Novel Small Molecule Inhibitors of Cancer Stem Cell Signaling Pathways

Abetov, Danysh; Mustapova, Zhanar; Saliev, Timur; Bulanin, Denis; Batyrbekov, Kanat; Gilman, Charles P. (Stem Cell Reviews and Reports, 2015-12-01)

The main aim of oncologists worldwide is to understand and then intervene in the primary tumor initiation and propagation mechanisms. This is essential to allow targeted elimination of cancer cells without altering normal ...