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ANTIGEN SPECIFICITY ENHANCES DISEASE CONTROL BY TREGS IN VITILIGO

Mukhatayev, Zhussipbek; Dellacecca, Emilia R.; Cosgrove, Cormac; Shivde, Rohan; Jaishankar, Dinesh; Pontarolo-Maag, Katherine; Eby, Jonathan M.; Henning, Steven W.; Ostapchuk, Yekaterina O.; Cedercreutz, Kettil; Issanov, Alpamys; Mehrotra, Shikhar; Overbeck, Andreas; Junghans, Richard P.; Leventhal, Joseph R.; Le Poole, I. Caroline (Frontiers Media, 2020-12-01)

Vitiligo is an autoimmune skin disease characterized by melanocyte destruction. Regulatory T cells (Tregs) are greatly reduced in vitiligo skin, and replenishing peripheral skin Tregs can provide protection against ...
ANTI-INFLAMMATORY, ANTIOXIDANT, AND ANTI-ATHEROSCLEROTIC EFFECTS OF NATURAL SUPPLEMENTS ON PATIENTS WITH FMF-RELATED AA AMYLOIDOSIS: A NON-RANDOMIZED 24-WEEK OPEN-LABEL INTERVENTIONAL STUDY

Romano, Micol; Garcia-Bournissen, Facundo; Piskin, David; Rodoplu, Ulkumen; Piskin, Lizzy; Elzagallaai, Abdelbaset A.; Tuncer, Tunc; Sezer, Siren; Ucuncuoglu, Didar; Honca, Tevfik; Poddighe, Dimitri; Yavuz, Izzet; Stenvinkel, Peter; Yilmaz, Mahmut Ilker; Demirkaya, Erkan (life, 2022)

We aimed to evaluate the effect of a combination of natural products on parameters related to inflammation, endothelial dysfunction, and oxidative stress in a cohort of familial Mediterranean fever (FMF) patients with ...
Antimicrobial activity of silver nanoparticles incorporated in a cryogel matrix

Illsley, Matthew; Bower, Cressida; Akhmetova, Alma; Kulsharova, Gulsim; Saliev, Timur; Nurgozhin, Talgat; Mikhalovsky, S. V. (27, h European Conference on Biomaterials, Krakow, Poland, 2015-09)

Hospital acquired infections are a major financial and societal burden with high mortality, morbidity and cost. Such infections are caused by a number of pathogenic and opportunistic bacteria, many of which are resistant to ...
Antimicrobial susceptibility of Brucella melitensis in Kazakhstan

Ramankulov, Yerlan; Shevtsov, Alexandr; Syzdykov, Marat; Kuznetsov, Andrey; Shevtsova, Elena; Berdimuratova, Kalysh; Kasim, Mukanov (Nazarbayev University School of Sciences and Humanities, 2017-12-28)

Background: Kazakhstan belongs to countries with a high level of brucellosis among humans and farm animals. Although antibiotic therapy is the main way to treat acute brucellosis in humans there is still little information ...
Antioxidant and anti-inflammatory properties of plant extract from Limonium Gmelinii

Tsoy, А.; Abzhanova, E.; Turgambayeva, A.; Zhussupova, G.; Shalakhmetova, T.; Nurkenov, T.; Askarova, Sh. (National Laboratory Astana, Nazarbayev University, 2017-09-15)
Antioxidant properties of grape polyphenol concentrate from Kazakhstan region

Yermekbayeva, B.; Shulgau, Z.; Sergazy, Sh.; Kabdullina, A.; Khassenbekova, Zh.; Tritek, V.; Abuova, G.; Zhaugasheva, S.; Gulyayev, A.; Nurgozhin, T. (2016-05)

It is believed that the antioxidant effects are widespread among plant polyphenols. Antioxidant effect is associated with main biological activities of polyphenols. Objective. To describe the antioxidant effect of grape ...
ANTIPROLIFERATIVE AND CYTOTOXIC ACTIVITY OF GERANIACEAE PLANT EXTRACTS AGAINST FIVE TUMOR CELL LINES

Sergazy, Shynggys; Vetrova, Anastassiya; Orhan, Ilkay Erdogan; Deniz, Fatma Sezer Senol; Kahraman, Ahmet; Zhang, Jian-Ye; Aljofan, Mohamad (Future science, 2021)

Several plant species of the genera Geranium and Erodium were extracted and screened against five tumor cell lines for their potential antitumor activities. Out of the tested species, four showed potential antitumor ...
ANTIRADICAL AND CYTOPROTECTIVE PROPERTIES OF ALLIUM NUTANS L. HONEY AGAINST CCL4-INDUCED LIVER DAMAGE IN RATS

Sergazy, Shynggys; Gulyayev, Alexander; Amangeldiyeva, Aidana; Nurgozhina, Ayaulym; Nurgaziyev, Madiyar; Shulgau, Zarina; Chulenbayeva, Laura; Khassenbekova, Zhanagul; Kushugulova, Almagul; Aljofan, Mohamad (Frontiers in Pharmacology, 2021-09-20)

The aim of this study is determine the in vitro and in vivo antiradical properties and the cytoprotective activity of Allium nutans L. honey extract. The antiradical properties of the extracts were investigated in rabbit ...
Antiresonances and Ultrafast Resonances in a Twin Photonic Oscillator

Kominis, Yannis; Choquette, Kent D.; Bountis, Anastassios; Kovanis, Vassilios (Institute of Electrical and Electronics Engineers, 2019-02)

We consider the properties of the small-signal modulation response of symmetry-breaking phase-locked states of twin coupled semiconductor lasers. The extended stability and the varying asymmetry of these modes allows for ...
ANTIRETROVIRAL THERAPY RESISTANCE MUTATIONS AMONG HIV INFECTED PEOPLE IN KAZAKHSTAN

Mukhatayeva, Ainur; Mustafa, Aidana; Dzissyuk, Natalya; Issanov, Alpamys; Mukhatayev, Zhussipbek; Bayserkin, Bauyrzhan; Vermund, Sten H.; Ali, Syed (Scientific Reports, 2022)

In Kazakhstan, the number of people living with HIV (PLHIV) has increased steadily by 39% since 2010. Development of antiretroviral therapy (ART) resistance mutations (ARTRM) is a major hurdle in achieving effective treatment ...
Anti-vax movement and the challenge for primary care professionals

Crape, Byron (Nazarbayev University School of Medicine, 2018-10-24)
Antiviral activities of extremophilic actinomycetes extracts from Kazakhstan’s unique ecosystems against influenza viruses and paramyxoviruses

Abdukhakimova, Diyora; Issanov, Alpamys; Azizan, Azliyati; Berezin, V.; Trenozhnikova, Lyudmila; Bogoyavlenskiy, Andrey; Turmagambetova, Aizhan; Issanov, Alpamys (Elsevier, 2019-12-02)

Commercially available antiviral drugs, when used in the treatment of viral infections, do not always result in success. This is an urgent problem currently that needs to be addressed because several viruses including ...
Antiviral Resistance of Splenocytes in Aged Mice

Burster, Timo (Nazarbayev University School of Sciences and Humanities, 2017-03-30)

We compared the susceptibility to viral infection of splenocytes, isolated from young versus old CBA mice, and evaluated the antiviral actions of lactoferrin in splenocytes infected with Encephalomyocarditis virus (EMCV). ...
ANURIA SECONDARY TO HOT WEATHER-INDUCED HYPERURICAEMIA: DIAGNOSIS AND MANAGEMENT

Al-Tawheed, Adel R.; Al-Awadi, Khaleel A.; Kehinde, Elijah O.; Abdul-Halim, Hamdy; Al-Hunayan, Adel; Ali, Yousef; Mohammed, Akram H. (Annals of Saudi Medicine, 2003-09)

There is little information on the management of anuria secondary to severe volume depletion or as a rare manifestation of heat stroke in areas of the world with very hot summers. We present our experience with hot ...
A passive wireless tracking system for indoor assistive monitoring

Hee Kho, Yau; Soon Chong, Nguan; Caglar Kizilirmak, Refik (IEEE Computer Society, 2016)

This paper presents a design concept and implementation of an indoor passive tracking system that utilises an array of Wi-Fi transceivers, and without any electronic device or tag attached to the object being tracked. Such ...
APBioNet's annual International Conference on Bioinformatics (InCoB) returns to India in 2018

Schönbach, Christian; Ahmad, Shandar; Gromiha, Michael M.; Raghava, Gajendra P.S.; Ranganathan, Shoba (Nazarbayev University School of Sciences and Humanities, 2019-04-18)

InCoB, one of the largest annual bioinformatics conferences in the Asia-Pacific region since its launch in 2002, returned to New Delhi, India after 12 years, with a conference attendance of 314 delegates. The 2018 conference ...
A Penalty Method for Approximations of the Stationary Power-Law Stokes Problem

Lefton, Lew; Wei, Dongming (Electronic journal of differential equations, 2001)

We study approximations of the steady state Stokes problem governed by the power-law model for viscous incompressible non-Newtonian flow using the penalty formulation. We establish convergence and find error estimates.
A peripheral viewpoint on the land reform in the uzbek SSR (1924-1929)

Penati, B. (Nazarbayev University, 2014)

The land-and-water reform in the Uzbek SSR was the most important mobilization initiative that the Bolshevik regime carried out in the 1920s. Its impact in terms of land redistribution was small, but it generated consensus ...
A Personal View on a Zero Carbon Future

Winter, Axel (International Scientific and University Conference. "Climate Change and CO2 Emission Reduction" 12-13 July, 2017, 2017-07-12)
A perspective on future employability

Akdeniz, Alper (Nazarbayev University Graduate School of Education, 2015)

Our theme for this plenary session; Perceptions of Employability, Skills and Individual aspiration in a diversifying economy, is certainly a very interesting and important topic which deserves reflection.